Can Methylene Blue and Melatonin Stop Seizures?

TL;DR

A creator with temporal lobe epilepsy says he went from about nine seizures a day to zero within roughly three weeks after using methylene blue, high-dose melatonin, and red light therapy alongside care from Dr. John Lieurance. He frames these as mitochondria-supporting molecules. The video explicitly states it is not medical advice and he is not a doctor.

Transcript

this is the inside of my brain and this is a blue substance which might have saved my life and I'm going to show you how all this happened and how it might save the life of somebody that you know 9 months ago my brain was eating itself alive and I was having about nine seizures a day there were periods I didn't even know who my wife was this is my ... Read More

Key Insights

• The creator was diagnosed with temporal lobe epilepsy and a possible mesial temporal sclerosis, experiencing about nine seizures a day, severe memory loss, and periods where he did not recognize his own wife, with symptoms tracing back to 2019.
• The prescribed anti-seizure drug offered symptom control but nothing to reverse brain damage or address the underlying cause, and its most common listed side effect was seizures, which deepened his desperation.
• Methylene blue is described as a blue dye created in the 1800s to color fabrics, used to treat disease since around 1890, and historically the origin of the phrase 'magic bullet' in medicine.
• Mitochondria are described as microscopic power plants inside every cell that convert nutrients into ATP, and the creator claims nearly every chronic disease from diabetes to neurodegenerative disorders traces back to mitochondrial dysfunction.
• The creator claims methylene blue crosses the blood-brain barrier, supports neurons, sharpens memory and focus, balances neurotransmitters, and shields cells from oxidative stress, having discovered it through a YouTube short by Dr. John Lieurance.
• High-dose melatonin at 200 mg is presented as far more than a sleep aid, claimed to act as a powerful antioxidant, immune booster, and anti-inflammatory, with the creator asserting high doses cause no crash or rebound in the body's own production.
• Melatonin was taken as a suppository rather than orally because, per the video, the liver destroys most of an oral dose through what is called the first pass effect.
• The creator reports going from nine seizures a day to zero within about three weeks of the protocol, while the video and description repeatedly stress this is not medical advice and he is not a doctor.

Questions & Answers

Q: What is methylene blue and where did it come from?

According to the video, methylene blue is a blue dye originally created in the 1800s to dye fabrics. It has been used to treat disease since around 1890, and the creator says the term 'magic bullet' in medicine was first spoken to describe it. He notes its patent expired long ago, making it easy and cheap to produce. He claims it supports mitochondria, crosses the blood-brain barrier, aids neurons, sharpens memory and focus, and shields cells from oxidative stress.

Q: How did the creator's brain disease and seizures start?

The creator says the condition started around 2019 when he blacked out for about a minute and a half in front of his parents and had amnesia for the event, followed by roughly a hundred more episodes over the next year. Because the seizures came with amnesia, he was not fully aware of them, and people had reportedly seen him have them for about three years. He was diagnosed with temporal lobe epilepsy and a possible mesial temporal sclerosis.

Q: What are mitochondria and why do they matter for brain health?

The video describes mitochondria as microscopic power plants inside every cell of the body, responsible for generating the electricity that fuels every function. They convert nutrients into ATP, the energy that powers everything from muscle movement to brain activity. The creator claims almost every chronic disease, from diabetes to neurodegenerative disorders, can trace its roots back to mitochondrial dysfunction, while also saying mitochondria are the beginning of health, which is why he focused his recovery there.

Q: How much melatonin did the creator take and why so much?

The creator says he took melatonin in doses of 200 mg, far above the roughly 2 mg pills sold at drugstores for sleep. He presents high-dose melatonin as a powerful antioxidant, immune booster, and anti-inflammatory that can help repair the brain, claiming high doses do not change the body's own melatonin production and cause no crash or rebound. He notes what he described was only about three percent of what he claims it can do.

Q: Why did the creator take melatonin as a suppository instead of a pill?

According to the video, he took melatonin as a suppository rather than orally because taking it by mouth means the liver destroys almost all of it through what he calls the first pass effect. By using a suppository, more of the dose reaches the body. He reports waking up the next day feeling better than in his twenties with perfect mind and memory, initially assuming it was a fluke until the improvement persisted over about three weeks.

Q: What results did the creator claim from the protocol?

The creator reports that after using methylene blue, high-dose melatonin, and red light therapy alongside care from Dr. John Lieurance, he went from about nine seizures a day to zero within roughly three weeks. He describes waking feeling better than in his twenties with restored memory. He frames the outcome emotionally, saying his kids were going to have a father. The video and description stress this is his personal account and not medical advice.

Q: Who is Dr. John Lieurance in this story?

Dr. John Lieurance is the doctor the creator first saw in a YouTube short discussing neurology, mitochondria, and methylene blue. Described as a chiropractor and neurologist who uses alternative approaches to brain health, he runs a clinic in Sarasota. The creator tracked him down, began texting him, invited him to speak to his VIP coaching clients, and traveled to his clinic in mid-August, where he learned about methylene blue, melatonin, and red light therapy over multiple days.

Q: Why does the creator say doctors do not tell patients about methylene blue?

The creator argues that methylene blue is not promoted because it is not sexy, not expensive, and its patent expired long ago, so it is cheap to make and does not generate significant profit for big companies. He concludes the doctors he spoke with were not lying but simply never received education on it, despite what he calls well-reviewed and well-documented research spanning over a hundred years. The video repeatedly disclaims that it is not medical advice.

Summary & Key Takeaways

• Nine months before filming, the creator's brain was, in his words, eating itself alive, causing about nine seizures a day, amnesia, and failure to recognize his wife and family. Diagnosed with temporal lobe epilepsy and possible mesial temporal sclerosis, he was prescribed a drug that only managed symptoms and listed seizures as its most common side effect.

• Desperate, he read roughly a thousand research papers and watched a hundred videos on brain health. On a flight he saw a YouTube short by Dr. John Lieurance discussing mitochondria and methylene blue, tracked him down, and visited his Sarasota clinic, where he learned about methylene blue, high-dose melatonin, and red light therapy.

• Methylene blue is framed as an inexpensive, off-patent 1800s dye supporting mitochondria and neurons, while 200 mg melatonin is presented as a potent antioxidant and anti-inflammatory. The creator says he went from nine seizures a day to zero within about three weeks. The video stresses it is not medical advice.