genken

genken

@genken

Hibernation/Hypothalamus/Sympathetic Neuron/PostDoc/movies

Joined Jan 19, 2023

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Meningeal interleukin-17-producing T cells mediate cognitive impairment in a mouse model of salt-sensitive hypertension - Nature Neuroscience

www.nature.com/articles/s41593-023-01497-z

immunology

Jan 16, 2024

11

Decoding the language of immunity

www.science.org/doi/10.1126/science.adn1067

immunology
basic research

Jan 16, 2024

55

Spatial IMA1 regulation restricts root iron acquisition on MAMP perception - Nature

www.nature.com/articles/s41586-023-06891-y

Jan 16, 2024

22

Causes and consequences of pre-hibernation body mass in golden-mantled ground squirrels (Callospermophilus lateralis)

academic.oup.com/jmammal/advance-article/doi/10.1093/jmammal/gyad131/7517779?login=true

hibernation

Jan 16, 2024

98

Mitochondrial Targeting against Alzheimer’s Disease: Lessons from Hibernation

www.mdpi.com/2073-4409/13/1/12

冬眠研究の意義

Jan 13, 2024

1

Torpor: A whole-brain view of the underlying neural network

www.cell.com/current-biology/pdf/S0960-9822(23)01638-X.pdf

積読
hibernation
torpor

Jan 13, 2024

1

prof. dr. R.H. (Rob) Henning

www.rug.nl/staff/r.h.henning/

hibernation
冬眠競合ラボ

Jan 11, 2024

1

Synthetic torpor triggers a regulated mechanism in the rat brain, favoring the reversibility of Tau protein hyperphosphorylation

www.frontiersin.org/articles/10.3389/fphys.2023.1129278/full

Jan 11, 2024

1

Torpor enhances synaptic strength and restores memory performance in a mouse model of Alzheimer’s disease - Scientific Reports

www.nature.com/articles/s41598-021-94992-x

冬眠研究の意義
積読
hibernation
alzheimer disease

Jan 11, 2024

1

Proteome census upon nutrient stress reveals Golgiphagy membrane receptors - Nature

www.nature.com/articles/s41586-023-06657-6

読み会

Jan 10, 2024

165

Lipid-anchored proteasomes control membrane protein homeostasis

www.science.org/doi/10.1126/sciadv.adj4605

Jan 9, 2024

11

Synapse-specific burst coding sustained by local axonal translation

www.cell.com/neuron/fulltext/S0896-6273(23)00767-5

積読
Neuron

Jan 9, 2024

11

Control and coding of pupil size by hypothalamic orexin neurons - Nature Neuroscience

www.nature.com/articles/s41593-023-01365-w

積読
sleep
hypothalamus
Nat Neurosci

Jan 9, 2024

11

TFEB–vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy - Nature Neuroscience

www.nature.com/articles/s41593-023-01494-2

積読
lysosome
tau

Jan 9, 2024

1

Esr1+ hypothalamic-habenula neurons shape aversive states - Nature Neuroscience

www.nature.com/articles/s41593-023-01367-8

hypothalamus
積読
scRNAseq

Jan 9, 2024

11

The medial preoptic area mediates depressive-like behaviors induced by ovarian hormone withdrawal through distinct GABAergic projections - Nature Neuroscience

www.nature.com/articles/s41593-023-01397-2

preoptic area
積読
hypothalamus

Jan 9, 2024

11

Using temperature to analyze the neural basis of a time-based decision - Nature Neuroscience

www.nature.com/articles/s41593-023-01378-5

積読
温度

Jan 9, 2024

11

A global view of aging and Alzheimer’s pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains - Nature Genetics

www.nature.com/articles/s41588-023-01572-y

alzheimer disease
積読
scRNAseq

Jan 9, 2024

11

Microglia enhance post-anesthesia neuronal activity by shielding inhibitory synapses - Nature Neuroscience

www.nature.com/articles/s41593-023-01537-8

積読
anethesia

Jan 9, 2024

11

Women’s neuroplasticity during gestation, childbirth and postpartum - Nature Neuroscience

www.nature.com/articles/s41593-023-01513-2

積読
養育行動

Jan 9, 2024

11

Updating the striatal–pallidal wiring diagram - Nature Neuroscience

www.nature.com/articles/s41593-023-01518-x

積読
神経回路

Jan 9, 2024

1

A tool kit of highly selective and sensitive genetically encoded neuropeptide sensors

www.science.org/doi/10.1126/science.abq8173

積読
Research tool

Jan 8, 2024

11

Structural visualization of transcription initiation in action

www.science.org/doi/10.1126/science.adi5120

転写

Jan 8, 2024

11

Pregnancy-responsive pools of adult neural stem cells for transient neurogenesis in mothers

www.science.org/doi/10.1126/science.abo5199

積読

Jan 8, 2024

11

Nesting chinstrap penguins accrue large quantities of sleep through seconds-long microsleeps

www.science.org/doi/10.1126/science.adh0771

sleep
積読

Jan 8, 2024

11

Tau in cerebrospinal fluid induces neuronal hyperexcitability and alters hippocampal theta oscillations - Acta Neuropathologica Communications

actaneurocomms.biomedcentral.com/articles/10.1186/s40478-023-01562-5

tau
alzheimer disease

Jan 8, 2024

11

Golgi fragmentation – One of the earliest organelle phenotypes in Alzheimer’s disease neurons

www.frontiersin.org/articles/10.3389/fnins.2023.1120086/full

alzheimer disease
tau

Jan 8, 2024

22

Unconventional secretion of tau by VAMP8 impacts its intra- and extracellular cleavage

www.frontiersin.org/articles/10.3389/fcell.2022.912118/full

tau secretion
tau

Jan 8, 2024

44

Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals

www.cell.com/cell/fulltext/S0092-8674(23)01176-5

積読
読み会候補

Jan 8, 2024

1

APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread

www.cell.com/cell/fulltext/S0092-8674(23)01315-6

積読
alzheimer disease

Jan 8, 2024

11

Stress granules plug and stabilize damaged endolysosomal membranes - Nature

www.nature.com/articles/s41586-023-06726-w

積読
読み会候補

Jan 8, 2024

1

Molecularly defined and spatially resolved cell atlas of the whole mouse brain - Nature

www.nature.com/articles/s41586-023-06808-9

scRNAseq
積読

Jan 8, 2024

1

Brain-wide correspondence of neuronal epigenomics and distant projections - Nature

www.nature.com/articles/s41586-023-06823-w

積読
scRNAseq

Jan 8, 2024

11

Gene expression of single cells mapped in tissue sections

www.nature.com/articles/d41586-023-03788-8

積読
scRNAseq

Jan 8, 2024

11

Conserved and divergent gene regulatory programs of the mammalian neocortex - Nature

www.nature.com/articles/s41586-023-06819-6

積読
evolution

Jan 8, 2024

1

Disease-specific tau filaments assemble via polymorphic intermediates - Nature

www.nature.com/articles/s41586-023-06788-w

alzheimer disease
Alzforum
tau structure

Jan 8, 2024

11

Large-scale cerebrospinal fluid proteomic analysis in Alzheimer’s disease patients reveals five molecular subtypes with distinct genetic risk profiles

www.medrxiv.org/content/10.1101/2023.05.10.23289793v1

Alzforum
alzheimer disease

Jan 8, 2024

11

difference between … of …(正しい)と、difference of … between …(誤用)をきちんと理解する | 或る特許翻訳者の書斎

jiyuugatanookite.com/patent/post-821-821.html

Jan 7, 2024

1

学術英語論文執筆のヒント | Uni-edit.net

www.uni-edit.net/japan/english-writing

英語
文法

Jan 7, 2024

1

【英語論文の書き方】第24回 because, since, as など 理由を表す表現 論文翻訳・英文校正 研究者専門の翻訳会社 ワールド翻訳サービス

www.worldts.com/english-writing/eigo-ronbun24/index.html

Jan 3, 2024

3

【英語文法】Due to と Because of の違い - データ分析メモと北欧生活

keita43a.hatenablog.com/entry/2019/10/09/181606

英語
文法

Jan 3, 2024

4

Endocytosed Cation-Independent Mannose 6-Phosphate Receptor Traffics via the Endocytic Recycling Compartment en Route to the trans-Golgi Network and a Subpopulation of Late Endosomes

www.molbiolcell.org/doi/10.1091/mbc.e03-07-0497

IGF2R

Dec 18, 2023

11

An Effector Domain Mutant of Arf6 Implicates Phospholipase D in Endosomal Membrane Recycling

www.molbiolcell.org/doi/10.1091/mbc.e05-06-0523

Arf6

Dec 16, 2023

33

Neuronal expression of CD22: Novel mechanism for inhibiting microglial proinflammatory cytokine production

onlinelibrary.wiley.com/doi/10.1002/glia.20009

CD22

Dec 12, 2023

11

Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D | Journal of Cell Biology | Rockefeller University Press

rupress.org/jcb/article/196/4/483/36778/Arf6-promotes-autophagosome-formation-via-effects

Arf6
N48RI
Arf6-PLD

Dec 12, 2023

75

The GDP-bound form of Arf6 is located at the plasma membrane

journals.biologists.com/jcs/article/117/11/2389/27697/The-GDP-bound-form-of-Arf6-is-located-at-the

Arf6

Dec 12, 2023

33

CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity

www.frontiersin.org/articles/10.3389/fimmu.2018.02235/full

CD22
積読

Dec 12, 2023

21

Hypersialylation is a common feature of neurofibrillary tangles and granulovacuolar degenerations in Alzheimer's disease and tauopathy brains

onlinelibrary.wiley.com/doi/10.1111/neup.12277

tau
sialylation

Dec 11, 2023

11

CD22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of B cells

www.ncbi.nlm.nih.gov/pmc/articles/PMC3024466/

CD22

Dec 11, 2023

11

Distinct Endocytic Mechanisms of CD22 (Siglec-2) and Siglec-F Reflect Roles in Cell Signaling and Innate Immunity

www.tandfonline.com/doi/full/10.1128/MCB.00383-07

Dec 11, 2023

3