genken

genken

@genken

Hibernation/Hypothalamus/Sympathetic Neuron/PostDoc/movies

Joined Jan 19, 2023

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How hibernation and hypothermia help to improve anticoagulant control

www.tandfonline.com/doi/full/10.4161/23328940.2014.967595

hibernation
冬眠研究の意義

Jul 12, 2023

1

plaza.umin.ac.jp/~beehappy/analgesia/method-ani-ephysi.html

Jul 9, 2023

1

APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge

www.sciencedirect.com/science/article/pii/S2211124723002073?via%3Dihub

読み会

Jul 7, 2023

11

A mosaic of new and old cell types

www.science.org/doi/10.1126/science.add9465

積読

Jul 7, 2023

11

Genetic Dissection of Neural Circuits: A Decade of Progress

www.cell.com/neuron/fulltext/S0896-6273(18)30246-0

積読

Jul 7, 2023

1

EASI-FISH for thick tissue defines lateral hypothalamus spatio-molecular organization

www.cell.com/cell/fulltext/S0092-8674(21)01339-8

hypothalamus
LHA

Jul 7, 2023

1

Circuit coordination of opposing neuropeptide and neurotransmitter signals - Nature

www.nature.com/articles/s41586-023-06246-7

積読

Jul 7, 2023

1

Glymphatic influx and clearance are accelerated by neurovascular coupling - Nature Neuroscience

www.nature.com/articles/s41593-023-01327-2

積読
Glymphatic system

Jul 7, 2023

1

Spatially resolved single-cell translatomics at molecular resolution

www.science.org/doi/10.1126/science.add3067

積読
Research tool

Jul 7, 2023

1

Early Alzheimer’s disease pathology in human cortex is associated with a transient phase of distinct cell states

www.biorxiv.org/content/10.1101/2023.06.03.543569v1.full

積読
alzheimer disease

Jul 7, 2023

1

Dynamic mapping of proteome trafficking within and between living cells by TransitID

www.cell.com/cell/fulltext/S0092-8674(23)00596-2

Jul 4, 2023

1

β-Amyloid (D54D2) XP® Rabbit mAb

www.cellsignal.jp/products/primary-antibodies/b-amyloid-d54d2-xp-rabbit-mab/8243

seminar
Ab

Jul 3, 2023

11

A kidney-brain neural circuit drives progressive kidney damage and heart failure - Signal Transduction and Targeted Therapy

www.nature.com/articles/s41392-023-01402-x

積読
Research tool
synapse tracer
JC

Jun 29, 2023

1

Sleep sculpts circuits in every species studied

www.cell.com/cell/fulltext/S0092-8674(23)00594-9

積読

Jun 27, 2023

1

Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients

www.science.org/doi/10.1126/scitranslmed.aam7621?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

読み会

Jun 23, 2023

53

Current Knowledge on Mammalian Phospholipase A1, Brief History, Structures, Biochemical and Pathophysiological Roles

www.mdpi.com/1420-3049/27/8/2487

PLA1A

Jun 20, 2023

22

The activation loop of PIP5K functions as a membrane sensor essential for lipid substrate processing

www.science.org/doi/10.1126/sciadv.1600925

PIP5K

Jun 20, 2023

11

Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis

www.mdpi.com/1422-0067/22/23/12685

PLA1A

Jun 19, 2023

11

PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria

www.ncbi.nlm.nih.gov/pmc/articles/PMC6757148/

PLA1A

Jun 19, 2023

11

阻害剤調製時に知っておきたい5つのポイント | M-hub(エムハブ)

m-hub.jp/biology/2683/176

Research tool

Jun 19, 2023

1

ARF6 regulates a plasma membrane pool of phosphatidylinositol(4,5)bisphosphate required for regulated exocytosis

rupress.org/jcb/article-standard/162/4/647/33350/ARF6-regulates-a-plasma-membrane-pool-of

Jun 17, 2023

54

Annexin V Assay Kits | MBLライフサイエンス

ruo.mbl.co.jp/bio/product/apoptosis/annexin.html

Jun 17, 2023

11

Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice

www.embopress.org/doi/full/10.15252/embr.202050219

Jun 16, 2023

1

Antiviral mechanism of preclinical antimalarial compounds possessing multiple antiviral activities

www.ncbi.nlm.nih.gov/pmc/articles/PMC8103717/

PLA1A

Jun 16, 2023

11

PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria

karger.com/jin/article/10/4/315/180107/PLA1A-Participates-in-the-Antiviral-Innate-Immune

PLA1A
knockdown

Jun 16, 2023

21

Chlorate: A reversible inhibitor of proteoglycan sulfation

www.sciencedirect.com/science/article/pii/0006291X88906948

Jun 15, 2023

11

INHIBITION BY NEOMYCIN OF POLYPHOSPHOINOSITIDE TURNOVER IN SUBCELLULAR FRACTIONS OF GUINEA‐PIG CEREBRAL CORTEX IN VITRO

onlinelibrary.wiley.com/doi/epdf/10.1111/j.1471-4159.1976.tb00318.x

Jun 15, 2023

11

Secretion of Tau via an Unconventional Non-vesicular Mechanism

www.sciencedirect.com/science/article/pii/S2211124718316826

tau
tau secretion

Jun 14, 2023

51

Amyloid Jungle: Plaque Fibrils Mesh With All Manner of Vesicles, Membranes | ALZFORUM

www.alzforum.org/news/research-news/amyloid-jungle-plaque-fibrils-mesh-all-manner-vesicles-membranes

積読
Alzforum
alzheimer disease

Jun 14, 2023

Higher-Resolution Spatial Transcriptomics Maps Mayhem Near Plaques | ALZFORUM

www.alzforum.org/news/research-news/higher-resolution-spatial-transcriptomics-maps-mayhem-near-plaques

積読
alzheimer disease
Alzforum

Jun 14, 2023

The Na,K-ATPase acts upstream of phosphoinositide PI(4,5)P2 facilitating unconventional secretion of Fibroblast Growth Factor 2 - Communications Biology

www.nature.com/articles/s42003-020-0871-y

積読
FGF2

Jun 13, 2023

11

FGF2 and IL-1β – explorers of unconventional secretory pathways at a glance

journals.biologists.com/jcs/article/133/21/jcs250449/226195/FGF2-and-IL-1-explorers-of-unconventional

UPS
FGF2
tau secretion

Jun 13, 2023

51

A Direct Role for ATP1A1 in Unconventional Secretion of Fibroblast Growth Factor 2

www.sciencedirect.com/science/article/pii/S0021925820492105?via%3Dihub

積読
FGF2

Jun 13, 2023

Key steps in unconventional secretion of fibroblast growth factor 2 reconstituted with purified components

elifesciences.org/articles/28985

積読
FGF2

Jun 13, 2023

Unconventional Secretion of Fibroblast Growth Factor 2 Is Mediated by Direct Translocation across the Plasma Membrane of Mammalian Cells

www.sciencedirect.com/science/article/pii/S0021925818445735?via%3Dihub

積読
FGF2

Jun 13, 2023

Single event visualization of unconventional secretion of FGF2 | Journal of Cell Biology | Rockefeller University Press

rupress.org/jcb/article/218/2/683/120492/Single-event-visualization-of-unconventional

積読
FGF2

Jun 13, 2023

A direct gateway into the extracellular space: Unconventional secretion of FGF2 through self-sustained plasma membrane pores

www.sciencedirect.com/science/article/pii/S1084952117301003?via%3Dihub

積読
FGF2

Jun 13, 2023

FRMD4A–cytohesin signaling modulates the cellular release of tau

journals.biologists.com/jcs/article/129/10/2003/55565/FRMD4A-cytohesin-signaling-modulates-the-cellular

tau secretion
tau
check up later
Arf6

Jun 13, 2023

66

Phosphatidylinositol 4,5-Bisphosphate (PI(4,5)P2)-dependent Oligomerization of Fibroblast Growth Factor 2 (FGF2) Triggers the Formation of a Lipidic Membrane Pore Implicated in Unconventional Secretion

www.sciencedirect.com/science/article/pii/S0021925820477890?via%3Dihub

FGF2
UPS
tau secretion

Jun 13, 2023

2

Trans-regulation of oligodendrocyte myelination by neurons through small GTPase Arf6-regulated secretion of fibroblast growth factor-2 - Nature Communications

www.nature.com/articles/ncomms5744

tau
積読
tau secretion
Arf6
check up later

Jun 12, 2023

21

低分子量Gタンパク質Arf6の個体における多彩な生理機能

seikagaku.jbsoc.or.jp/10.14952/SEIKAGAKU.2016.880078/data/index.html

tau
tau secretion
Arf6

Jun 12, 2023

243

ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles

www.sciencedirect.com/science/article/pii/S0960982209017722?via%3Dihub

tau
tau secretion
積読
Arf6
check up later
ectosome

Jun 12, 2023

1

マイクロRNAをより詳細にカタログ化 | 理化学研究所

www.riken.jp/press/2017/20170822_1/

database
Research tool

Jun 12, 2023

1

マイクロRNA:生合成調節機構と遺伝子発現調節ネットワークの理解

seikagaku.jbsoc.or.jp/10.14952/SEIKAGAKU.2015.870413/data/index.html

seminar
Research tool

Jun 12, 2023

11

In Amyloid Cascade, Do Reactive Astrocytes Bridge Plaques and Tangles? | ALZFORUM

www.alzforum.org/news/research-news/amyloid-cascade-do-reactive-astrocytes-bridge-plaques-and-tangles

tau

Jun 12, 2023

22

Multiomic Analysis Shows Lysosomes Need Retromer to Stay Healthy | ALZFORUM

www.alzforum.org/news/research-news/multiomic-analysis-shows-lysosomes-need-retromer-stay-healthy

alzheimer disease

Jun 12, 2023

85

Immobility-associated thromboprotection is conserved across mammalian species from bear to human

www.science.org/doi/10.1126/science.abo5044

hibernation

Jun 11, 2023

65

Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens

www.science.org/doi/10.1126/science.adh7699

Research tool
積読

Jun 11, 2023

21

The Greatest Films of All Time

www.bfi.org.uk/sight-and-sound/greatest-films-all-time

movie
hobby

Jun 11, 2023

Mechanisms of Endocytosis

www.annualreviews.org/doi/10.1146/annurev.biochem.78.081307.110540?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed

Jun 10, 2023

41