Secretion of Tau via an Unconventional Non-vesicular Mechanism

www.sciencedirect.com/science/article/pii/S2211124718316826

Amyloid Jungle: Plaque Fibrils Mesh With All Manner of Vesicles, Membranes | ALZFORUM

www.alzforum.org/news/research-news/amyloid-jungle-plaque-fibrils-mesh-all-manner-vesicles-membranes

Higher-Resolution Spatial Transcriptomics Maps Mayhem Near Plaques | ALZFORUM

www.alzforum.org/news/research-news/higher-resolution-spatial-transcriptomics-maps-mayhem-near-plaques

The Na,K-ATPase acts upstream of phosphoinositide PI(4,5)P2 facilitating unconventional secretion of Fibroblast Growth Factor 2 - Communications Biology

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FGF2 and IL-1β – explorers of unconventional secretory pathways at a glance

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A Direct Role for ATP1A1 in Unconventional Secretion of Fibroblast Growth Factor 2

www.sciencedirect.com/science/article/pii/S0021925820492105?via%3Dihub

Key steps in unconventional secretion of fibroblast growth factor 2 reconstituted with purified components

elifesciences.org/articles/28985

Unconventional Secretion of Fibroblast Growth Factor 2 Is Mediated by Direct Translocation across the Plasma Membrane of Mammalian Cells

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Single event visualization of unconventional secretion of FGF2 | Journal of Cell Biology | Rockefeller University Press

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A direct gateway into the extracellular space: Unconventional secretion of FGF2 through self-sustained plasma membrane pores

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FRMD4A–cytohesin signaling modulates the cellular release of tau

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Phosphatidylinositol 4,5-Bisphosphate (PI(4,5)P2)-dependent Oligomerization of Fibroblast Growth Factor 2 (FGF2) Triggers the Formation of a Lipidic Membrane Pore Implicated in Unconventional Secretion

www.sciencedirect.com/science/article/pii/S0021925820477890?via%3Dihub

Trans-regulation of oligodendrocyte myelination by neurons through small GTPase Arf6-regulated secretion of fibroblast growth factor-2 - Nature Communications

www.nature.com/articles/ncomms5744

低分子量Gタンパク質Arf6の個体における多彩な生理機能

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ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles

www.sciencedirect.com/science/article/pii/S0960982209017722?via%3Dihub

マイクロRNAをより詳細にカタログ化 | 理化学研究所

www.riken.jp/press/2017/20170822_1/

マイクロRNA：生合成調節機構と遺伝子発現調節ネットワークの理解

seikagaku.jbsoc.or.jp/10.14952/SEIKAGAKU.2015.870413/data/index.html

In Amyloid Cascade, Do Reactive Astrocytes Bridge Plaques and Tangles? | ALZFORUM

www.alzforum.org/news/research-news/amyloid-cascade-do-reactive-astrocytes-bridge-plaques-and-tangles

Multiomic Analysis Shows Lysosomes Need Retromer to Stay Healthy | ALZFORUM

www.alzforum.org/news/research-news/multiomic-analysis-shows-lysosomes-need-retromer-stay-healthy

Immobility-associated thromboprotection is conserved across mammalian species from bear to human

www.science.org/doi/10.1126/science.abo5044

Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens

www.science.org/doi/10.1126/science.adh7699

The Greatest Films of All Time

www.bfi.org.uk/sight-and-sound/greatest-films-all-time

Mechanisms of Endocytosis

www.annualreviews.org/doi/10.1146/annurev.biochem.78.081307.110540?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed

www.jstage.jst.go.jp/article/oleoscience/13/10/13_493/_pdf/-char/ja

ARF6 and Rab11 as intrinsic regulators of axon regeneration

www.tandfonline.com/doi/full/10.1080/21541248.2018.1457914

Single-cell spatial proteomic imaging for human neuropathology - Acta Neuropathologica Communications

actaneurocomms.biomedcentral.com/articles/10.1186/s40478-022-01465-x

Single-cell spatial proteomic analysis by multiplexed imaging enables identification of microglial heterogeneity in Alzheimer’s disease human brain

www.researchsquare.com/article/rs-2870341/v1

Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease

onlinelibrary.wiley.com/doi/full/10.1002/ana.26620

Commentary: BAG3 as a Mediator of Endosome Function and Tau Clearance

www.sciencedirect.com/science/article/pii/S0306452222002317?via%3Dihub

Abnormal Tau Slips into Synapses Long Before Tangles Form | ALZFORUM

www.alzforum.org/news/research-news/abnormal-tau-slips-synapses-long-tangles-form

Hi-Res Spatial Proteomics Uncovers Aspects of Alzheimer’s Disease Pathology | ALZFORUM

www.alzforum.org/news/research-news/hi-res-spatial-proteomics-uncovers-aspects-alzheimers-disease-pathology

Dynamic RNA Regulation in the Brain Underlies Physiological Plasticity in a Hibernating Mammal

www.frontiersin.org/articles/10.3389/fphys.2020.624677/full

Long-read isoform sequencing reveals tissue-specific isoform expression between active and hibernating brown bears (Ursus arctos)

www.ncbi.nlm.nih.gov/pmc/articles/PMC9210309/

比較ゲノム配列解析〜冬眠哺乳類で保存性の高い遺伝子群の同定

forum.hibernationbiology.jp/threads/view/9

マウス休眠過程での血中グルコース濃度変化

forum.hibernationbiology.jp/threads/view/3

シリアンハムスター肝細胞の低温耐性に食餌由来のビタミンEが関与する

forum.hibernationbiology.jp/threads/view/1

ジュウサンセンジリスの夏〜冬〜深冬眠〜中途覚醒〜春の遺伝子発現変化

forum.hibernationbiology.jp/threads/view/6

Guide to a Postdoc

ubadahsabbagh.com/guide-to-postdoc.php

Yuki FURUSE 古瀬祐気さんはTwitterを使っています

twitter.com/ykfrs1217/status/1661309276277866496

Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation | Proceedings of the National Academy of Sciences

www.pnas.org/doi/10.1073/pnas.2108870119

Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway

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Syntaxins 6 and 8 facilitate tau into secretory pathways

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Uncovering tau in wasteosomes (corpora amylacea) of Alzheimer’s disease patients

www.frontiersin.org/articles/10.3389/fnagi.2023.1110425/full

Clearance of intracellular tau protein from neuronal cells via VAMP8-induced secretion

www.sciencedirect.com/science/article/pii/S0021925817506596?via%3Dihub

Botulinum neurotoxin A modulates the axonal release of pathological tau in hippocampal neurons

www.sciencedirect.com/science/article/pii/S004101012300096X?via%3Dihub

Metabotropic Glutamate Receptors Modulate Exocytotic Tau Release and Propagation

jpet.aspetjournals.org/content/383/2/117

Evolutionary constraint and innovation across hundreds of placental mammals

www.science.org/doi/10.1126/science.abn3943?utm_campaign=SciMag&utm_source=Twitter&utm_medium=ownedSocial

Seasonal and state-dependent changes in brain TRH receptors in hibernating ground squirrels - PubMed

pubmed.ncbi.nlm.nih.gov/1322229/

Arousal following intra-preoptic area administration of naltrexone, ICI 174864 or nor-BNI in hibernating ground squirrels - PubMed

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Thyrotropin-releasing hormone induced thermogenesis in Syrian hamsters: site of action and receptor subtype - PubMed

pubmed.ncbi.nlm.nih.gov/15781042/

Spatial and temporal activation of brain regions in hibernation: c-fos expression during the hibernation bout in thirteen-lined ground squirrel - PubMed

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