Endolysosomal degradation of Tau and its role in glucocorticoid‐driven hippocampal malfunction

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Fluorescent Proteins 101: Fluorescent Protein Timers

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ガヤの日記

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Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation

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Spatial atlas of the mouse central nervous system at molecular resolution - Nature

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The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C

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Glycinergic transmission in the mammalian retina

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Associations of plasma soluble CD22 levels with brain amyloid burden and cognitive decline in Alzheimer’s disease

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Mechanism of gating and partial agonist action in the glycine receptor

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CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

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CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity - Nature Immunology

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Internalization of the Lymphocytic Surface Protein CD22 Is Controlled by a Novel Membrane Proximal Cytoplasmic Motif *

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CD22: an inhibitory enigma

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The Ligand-binding Domain of CD22 Is Needed for Inhibition of the B Cell Receptor Signal, as Demonstrated by a Novel Human CD22-specific Inhibitor Compound | Journal of Experimental Medicine | Rockefeller University Press

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Induction of a torpor-like hypothermic and hypometabolic state in rodents by ultrasound - Nature Metabolism

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The chloride anion as a signalling effector

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Simultaneous intracellular chloride and pH measurements using a GFP-based sensor - Nature Methods

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A Superfolder Green Fluorescent Protein-Based Biosensor Allows Monitoring of Chloride in the Endoplasmic Reticulum

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Simultaneous two-photon imaging of intracellular chloride concentration and pH in mouse pyramidal neurons in vivo | Proceedings of the National Academy of Sciences

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Impaired Glycine Receptor Trafficking in Neurological Diseases

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Glycinergic Signaling in Macrophages and Its Application in Macrophage-Associated Diseases

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Modulators of the Inhibitory Glycine Receptor

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The impact of human hyperekplexia mutations on glycine receptor structure and function - Molecular Brain

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The genetics of hyperekplexia: more than startle!

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Native glycine receptor subtypes and their physiological roles

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DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon | Journal of Cell Biology | Rockefeller University Press

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Keratinocyte-associated protein 2 is a bona fide subunit of the mammalian oligosaccharyltransferase

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A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells - Nature Communications

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LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits - Nature Aging

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Formation of Disulfide Bridges Drives Oligomerization, Membrane Pore Formation, and Translocation of Fibroblast Growth Factor 2 to Cell Surfaces

www.sciencedirect.com/science/article/pii/S0021925819819865

Distinct spatial maps and multiple object codes in the lateral entorhinal cortex

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WNT5A - Protein Wnt-5a - Homo sapiens (Human) | UniProtKB | UniProt

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TRIM11 protects against tauopathies and is down-regulated in Alzheimer’s disease

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Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist | Proceedings of the National Academy of Sciences

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Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer’s disease - Nature Communications

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Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area

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Warm-Sensitive Neurons that Control Body Temperature

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Seasonal decrease in thermogenesis and increase in vasoconstriction explain seasonal response to N6‐cyclohexyladenosine‐induced hibernation in the Arctic ground squirrel (Urocitellus parryii)

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Clock Gene Expression in the Suprachiasmatic Nucleus of Hibernating Arctic Ground Squirrels - Tomoko Ikeno, Cory T. Williams, C. Loren Buck, Brian M. Barnes, Lily Yan, 2017

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Neuronal Activity in the Hibernating Brain

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Gene Expression in the Brain across the Hibernation Cycle

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Berlin-Hamster-Single-Cell-Consortium · GitHub

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Spatial and temporal activation of brain regions in hibernation: c‐fos expression during the hibernation bout in thirteen‐lined ground squirrel

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C-fos mRNA increases in the ground squirrel suprachiasmatic nucleus during arousal from hibernation

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Hypothalamic orexinergic neuron changes during the hibernation of the Syrian hamster

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Gene Expression in the Brain across the Hibernation Cycle

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Tau Propagation Surprise: It Might Travel Retrogradely | ALZFORUM

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Parallel Accelerated Evolution in Distant Hibernators Reveals Candidate Cis Elements and Genetic Circuits Regulating Mammalian Obesity

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