Spatially resolved single-cell translatomics at molecular resolution

www.science.org/doi/10.1126/science.add3067

Early Alzheimer’s disease pathology in human cortex is associated with a transient phase of distinct cell states

www.biorxiv.org/content/10.1101/2023.06.03.543569v1.full

Dynamic mapping of proteome trafficking within and between living cells by TransitID

www.cell.com/cell/fulltext/S0092-8674(23)00596-2

β-Amyloid (D54D2) XP® Rabbit mAb

www.cellsignal.jp/products/primary-antibodies/b-amyloid-d54d2-xp-rabbit-mab/8243

A kidney-brain neural circuit drives progressive kidney damage and heart failure - Signal Transduction and Targeted Therapy

www.nature.com/articles/s41392-023-01402-x

Sleep sculpts circuits in every species studied

www.cell.com/cell/fulltext/S0092-8674(23)00594-9

Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients

www.science.org/doi/10.1126/scitranslmed.aam7621?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

Current Knowledge on Mammalian Phospholipase A1, Brief History, Structures, Biochemical and Pathophysiological Roles

www.mdpi.com/1420-3049/27/8/2487

The activation loop of PIP5K functions as a membrane sensor essential for lipid substrate processing

www.science.org/doi/10.1126/sciadv.1600925

Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis

www.mdpi.com/1422-0067/22/23/12685

PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria

www.ncbi.nlm.nih.gov/pmc/articles/PMC6757148/

阻害剤調製時に知っておきたい5つのポイント | M-hub（エムハブ）

m-hub.jp/biology/2683/176

ARF6 regulates a plasma membrane pool of phosphatidylinositol(4,5)bisphosphate required for regulated exocytosis

rupress.org/jcb/article-standard/162/4/647/33350/ARF6-regulates-a-plasma-membrane-pool-of

Annexin V Assay Kits | MBLライフサイエンス

ruo.mbl.co.jp/bio/product/apoptosis/annexin.html

Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice

www.embopress.org/doi/full/10.15252/embr.202050219

Antiviral mechanism of preclinical antimalarial compounds possessing multiple antiviral activities

www.ncbi.nlm.nih.gov/pmc/articles/PMC8103717/

PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria

karger.com/jin/article/10/4/315/180107/PLA1A-Participates-in-the-Antiviral-Innate-Immune

Chlorate: A reversible inhibitor of proteoglycan sulfation

www.sciencedirect.com/science/article/pii/0006291X88906948

INHIBITION BY NEOMYCIN OF POLYPHOSPHOINOSITIDE TURNOVER IN SUBCELLULAR FRACTIONS OF GUINEA‐PIG CEREBRAL CORTEX IN VITRO

onlinelibrary.wiley.com/doi/epdf/10.1111/j.1471-4159.1976.tb00318.x

Secretion of Tau via an Unconventional Non-vesicular Mechanism

www.sciencedirect.com/science/article/pii/S2211124718316826

Amyloid Jungle: Plaque Fibrils Mesh With All Manner of Vesicles, Membranes | ALZFORUM

www.alzforum.org/news/research-news/amyloid-jungle-plaque-fibrils-mesh-all-manner-vesicles-membranes

Higher-Resolution Spatial Transcriptomics Maps Mayhem Near Plaques | ALZFORUM

www.alzforum.org/news/research-news/higher-resolution-spatial-transcriptomics-maps-mayhem-near-plaques

The Na,K-ATPase acts upstream of phosphoinositide PI(4,5)P2 facilitating unconventional secretion of Fibroblast Growth Factor 2 - Communications Biology

www.nature.com/articles/s42003-020-0871-y

FGF2 and IL-1β – explorers of unconventional secretory pathways at a glance

journals.biologists.com/jcs/article/133/21/jcs250449/226195/FGF2-and-IL-1-explorers-of-unconventional

A Direct Role for ATP1A1 in Unconventional Secretion of Fibroblast Growth Factor 2

www.sciencedirect.com/science/article/pii/S0021925820492105?via%3Dihub

Key steps in unconventional secretion of fibroblast growth factor 2 reconstituted with purified components

elifesciences.org/articles/28985

Unconventional Secretion of Fibroblast Growth Factor 2 Is Mediated by Direct Translocation across the Plasma Membrane of Mammalian Cells

www.sciencedirect.com/science/article/pii/S0021925818445735?via%3Dihub

Single event visualization of unconventional secretion of FGF2 | Journal of Cell Biology | Rockefeller University Press

rupress.org/jcb/article/218/2/683/120492/Single-event-visualization-of-unconventional

A direct gateway into the extracellular space: Unconventional secretion of FGF2 through self-sustained plasma membrane pores

www.sciencedirect.com/science/article/pii/S1084952117301003?via%3Dihub

FRMD4A–cytohesin signaling modulates the cellular release of tau

journals.biologists.com/jcs/article/129/10/2003/55565/FRMD4A-cytohesin-signaling-modulates-the-cellular

Phosphatidylinositol 4,5-Bisphosphate (PI(4,5)P2)-dependent Oligomerization of Fibroblast Growth Factor 2 (FGF2) Triggers the Formation of a Lipidic Membrane Pore Implicated in Unconventional Secretion

www.sciencedirect.com/science/article/pii/S0021925820477890?via%3Dihub

Trans-regulation of oligodendrocyte myelination by neurons through small GTPase Arf6-regulated secretion of fibroblast growth factor-2 - Nature Communications

www.nature.com/articles/ncomms5744

低分子量Gタンパク質Arf6の個体における多彩な生理機能

seikagaku.jbsoc.or.jp/10.14952/SEIKAGAKU.2016.880078/data/index.html

ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles

www.sciencedirect.com/science/article/pii/S0960982209017722?via%3Dihub

マイクロRNAをより詳細にカタログ化 | 理化学研究所

www.riken.jp/press/2017/20170822_1/

マイクロRNA：生合成調節機構と遺伝子発現調節ネットワークの理解

seikagaku.jbsoc.or.jp/10.14952/SEIKAGAKU.2015.870413/data/index.html

In Amyloid Cascade, Do Reactive Astrocytes Bridge Plaques and Tangles? | ALZFORUM

www.alzforum.org/news/research-news/amyloid-cascade-do-reactive-astrocytes-bridge-plaques-and-tangles

Multiomic Analysis Shows Lysosomes Need Retromer to Stay Healthy | ALZFORUM

www.alzforum.org/news/research-news/multiomic-analysis-shows-lysosomes-need-retromer-stay-healthy

Immobility-associated thromboprotection is conserved across mammalian species from bear to human

www.science.org/doi/10.1126/science.abo5044

Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens

www.science.org/doi/10.1126/science.adh7699

The Greatest Films of All Time

www.bfi.org.uk/sight-and-sound/greatest-films-all-time

Mechanisms of Endocytosis

www.annualreviews.org/doi/10.1146/annurev.biochem.78.081307.110540?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed

www.jstage.jst.go.jp/article/oleoscience/13/10/13_493/_pdf/-char/ja

ARF6 and Rab11 as intrinsic regulators of axon regeneration

www.tandfonline.com/doi/full/10.1080/21541248.2018.1457914

Single-cell spatial proteomic imaging for human neuropathology - Acta Neuropathologica Communications

actaneurocomms.biomedcentral.com/articles/10.1186/s40478-022-01465-x

Single-cell spatial proteomic analysis by multiplexed imaging enables identification of microglial heterogeneity in Alzheimer’s disease human brain

www.researchsquare.com/article/rs-2870341/v1

Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease

onlinelibrary.wiley.com/doi/full/10.1002/ana.26620

Commentary: BAG3 as a Mediator of Endosome Function and Tau Clearance

www.sciencedirect.com/science/article/pii/S0306452222002317?via%3Dihub

Abnormal Tau Slips into Synapses Long Before Tangles Form | ALZFORUM

www.alzforum.org/news/research-news/abnormal-tau-slips-synapses-long-tangles-form

Hi-Res Spatial Proteomics Uncovers Aspects of Alzheimer’s Disease Pathology | ALZFORUM

www.alzforum.org/news/research-news/hi-res-spatial-proteomics-uncovers-aspects-alzheimers-disease-pathology