genken

genken

@genken

Hibernation/Hypothalamus/Sympathetic Neuron/PostDoc/movies

Joined Jan 19, 2023

8

Following

7

Followers

721

pages

1.30k

highlights

2.39k

views
M
W
F
May
Jun
Jul
Aug
Total Days:
Total Weeks:
250-Days 📚
108-Weeks 📚
Show All

A practical guide for single-cell transcriptome data analysis in neuroscience

www.sciencedirect.com/science/article/pii/S0168010225000653?via%3Dihub

積読
scRNAseq

May 16, 2025

1

Nicheformer: A Foundation Model for Single-Cell and Spatial Omics

papers.ssrn.com/sol3/papers.cfm?abstract_id=4803291

spatial TC
scRNAseq
Research tool

May 15, 2025

1

Reflex control of inflammation by sympathetic nerves, not the vagus

physoc.onlinelibrary.wiley.com/doi/10.1113/jphysiol.2013.268573

LPS
交感神経
spleen

May 12, 2025

1

Spatially resolved molecular and cellular atlas of the mouse brain

www.biorxiv.org/content/10.1101/2023.12.03.569501v1.full.pdf+html

scRNAseq
resource
spatial TC
development

May 10, 2025

1

Transcriptional conservation and evolutionary divergence of cell types across mammalian hypothalamus development

www.cell.com/developmental-cell/fulltext/S1534-5807(25)00156-X

hypothalamus
development
scRNAseq
resource
spatial TC

May 10, 2025

1

Using deep learning to quantify neuronal activation from single-cell and spatial transcriptomic data - Nature Communications

www.nature.com/articles/s41467-023-44503-5

spatial TC
neuronal activation
scRNAseq

May 2, 2025

1

Neuroendocrinology of Energy Homeostasis – Comparative Endocrinology

uw.pressbooks.pub/comparativeendocrinology/chapter/neuroendocrinology-of-energy-homeostasis/

体温調節
体温調節
体温制御
preoptic area
review

May 2, 2025

scRNAseq analysis functions. Developed using Seurat framework.

nmikolajewicz.github.io/scMiko/index.html

Seurat
scRNAseq
bioinformatics
Research tool

Apr 21, 2025

1

Single sample scoring of molecular phenotypes - BMC Bioinformatics

bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-018-2435-4

bioinformatics
scRNAseq
Research tool

Apr 17, 2025

1

3群以上で比較する前に必ず読もう!普通には検定できないって知ってますか?

toukeidesign.sozaiya-san.com/advance_stats14_3-group-test

統計
design

Apr 14, 2025

1

Autophagy and Akt-mTOR signaling display periodic oscillations during torpor-arousal cycles in oxidative skeletal muscle of Daurian ground squirrels (Spermophilus dauricus) - Journal of Comparative Physiology B

link.springer.com/article/10.1007/s00360-019-01245-5

autophagy
hibernation

Apr 11, 2025

1

Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation

www.sciencedirect.com/science/article/pii/S1550413123001249?pes=vor&utm_source=scopus&getft_integrator=scopus

autophagy
AgRP
積読

Apr 10, 2025

1

Mitophagy is required for brown adipose tissue mitochondrial homeostasis during cold challenge - Scientific Reports

www.nature.com/articles/s41598-018-26394-5

cold tolerance
BAT

Apr 10, 2025

Chronic cold exposure induces autophagy to promote fatty acid oxidation, mitochondrial turnover, and thermogenesis in brown adipose tissue

www.sciencedirect.com/science/article/pii/S2589004221004028?via%3Dihub

autophagy
cold tolerance
thermogenesis

Apr 10, 2025

1

A parabrachial-hypothalamic parallel circuit governs cold defense in mice - Nature Communications

www.nature.com/articles/s41467-023-40504-6

積読
体温調節
hypothalamus

Apr 8, 2025

1

Mouse embryonic stem cells embody organismal-level cold resistance

www.sciencedirect.com/science/article/pii/S2211124723009658?via%3Dihub

cold tolerance
hibernation

Apr 8, 2025

1

iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications

www.sciencedirect.com/science/article/pii/S0092867418302903?via%3Dihub

hibernation
cold tolerance

Apr 8, 2025

1

Coping with the stress: Expression of ATF4, ATF6, and downstream targets in organs of hibernating ground squirrels

www.sciencedirect.com/science/article/pii/S000398610800266X?via%3Dihub

hibernation
cold tolerance

Apr 8, 2025

1

RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration - Nature

www.nature.com/articles/nature14142

hibernation
cold tolerance
積読

Apr 8, 2025

Molecular Prerequisites for Diminished Cold Sensitivity in Ground Squirrels and Hamsters

www.sciencedirect.com/science/article/pii/S2211124717317503?via%3Dihub

hibernation
cold tolerance

Apr 8, 2025

1

AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1 - Nature Cell Biology

www.nature.com/articles/s41556-021-00642-9

hibernation
sympathetic nervous system
体温制御

Apr 8, 2025

1

Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death

www.biorxiv.org/content/10.1101/2024.07.25.605098v4

cold tolerance
hibernation

Apr 8, 2025

1

Graph-based Contrastive Learning Enables Unified Integration and Niche Transfer Across Single-Cell and Spatial Multi-Omics

www.biorxiv.org/content/10.1101/2025.02.19.638965v1

spatial TC
Research tool

Apr 8, 2025

1

mcDETECT: Decoding 3D Spatial Synaptic Transcriptomes with Subcellular-Resolution Spatial Transcriptomics

www.biorxiv.org/content/10.1101/2025.03.27.645744v1?ct=

spatial transcriptomics
Alzheimer's disease
Research tool

Apr 8, 2025

1

future/README_ja.md at develop · futureverse/future

github.com/futureverse/future/blob/develop/README_ja.md

R
future package
Research tool

Apr 2, 2025

11

Seasonal variation in thyrotropin-releasing hormone (TRH) content of different brain regions and the pineal in the mammalian hibernator, Citellus lateralis - PubMed

pubmed.ncbi.nlm.nih.gov/6801738/

Trh
hibernation

Mar 29, 2025

Single-cell transcriptomic analysis of the lateral hypothalamic area reveals molecularly distinct populations of inhibitory and excitatory neurons - Nature Neuroscience

www.nature.com/articles/s41593-019-0349-8

scRNAseq
LHA

Mar 29, 2025

Gene expression markers of identity classes — FindMarkers

satijalab.org/seurat/reference/findmarkers

seurat
scRNAseq
bioinformatics

Mar 28, 2025

11

RStudio Server

chromium3.cdb.riken.jp/

Feb 21, 2025

1

Spatial transcriptomics and single-nucleus RNA sequencing reveal a transcriptomic atlas of adult human spinal cord

elifesciences.org/articles/92046

spinal cord
spatial TC
scRNAseq

Feb 3, 2025

1

Neuroinflammation in the NTS is associated with changes in cardiovascular reflexes during systemic inflammation - Journal of Neuroinflammation

jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-019-1512-6

積読
交感神経
LPS-induced

Jan 15, 2025

1

Cold Exposure and the Metabolism of Mice, Men, and Other Wonderful Creatures | Physiology

journals.physiology.org/doi/full/10.1152/physiol.00002.2022?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org

寒冷暴露

Jan 10, 2025

Body temperature is a more important modulator of lifespan than metabolic rate in two small mammals - Nature Metabolism

www.nature.com/articles/s42255-022-00545-5

hibernation
積読

Jan 6, 2025

1

The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk - Nature Communications

www.nature.com/articles/s41467-024-54080-w

積読

Dec 26, 2024

Stochastic neuropeptide signals compete to calibrate the rate of satiation - Nature

www.nature.com/articles/s41586-024-08164-8

積読

Dec 26, 2024

1

A brain-to-gut signal controls intestinal fat absorption - Nature

www.nature.com/articles/s41586-024-07929-5

積読

Dec 26, 2024

1

Thermally induced neuronal plasticity in the hypothalamus mediates heat tolerance - Nature Neuroscience

www.nature.com/articles/s41593-024-01830-0

積読

Dec 26, 2024

1

A brain-to-liver signal mediates the inhibition of liver regeneration under chronic stress in mice - Nature Communications

www.nature.com/articles/s41467-024-54827-5

積読

Dec 26, 2024

Paraventricular hypothalamic RUVBL2 neurons suppress appetite by enhancing excitatory synaptic transmission in distinct neurocircuits - Nature Communications

www.nature.com/articles/s41467-024-53258-6

積読

Dec 26, 2024

1

Hypothalamus-sympathetic-liver axis mediates the early phase of stress-induced hyperglycemia in the male mice - Nature Communications

www.nature.com/articles/s41467-024-52815-3

積読

Dec 26, 2024

1

Excitation-inhibition imbalance in medial preoptic area circuits underlies chronic stress-induced depression-like states - Nature Communications

www.nature.com/articles/s41467-024-52727-2

積読

Dec 26, 2024

1

Light modulates glucose and lipid homeostasis via the sympathetic nervous system

www.science.org/doi/10.1126/sciadv.adp3284

積読

Dec 26, 2024

1

Identification of an ionic mechanism for ERα-mediated rapid excitation in neurons

www.science.org/doi/10.1126/sciadv.adp0696

積読

Dec 26, 2024

1

Neuromodulator and neuropeptide sensors and probes for precise circuit interrogation in vivo

www.science.org/doi/10.1126/science.adn6671

積読
review
Research tool

Dec 26, 2024

Presynaptic sensor and silencer of peptidergic transmission reveal neuropeptides as primary transmitters in pontine fear circuit

www.cell.com/cell/fulltext/S0092-8674(24)00709-8

積読

Dec 26, 2024

1

Structure-guided design of a peripherally restricted chemogenetic system

www.cell.com/cell/fulltext/S0092-8674(24)01275-3

積読

Dec 26, 2024

Transcriptomic cell-type specificity of local cortical circuits

www.cell.com/neuron/fulltext/S0896-6273(24)00651-2

積読

Dec 26, 2024

Leptin-activated hypothalamic BNC2 neurons acutely suppress food intake - Nature

www.nature.com/articles/s41586-024-08108-2

積読

Dec 26, 2024

1

A top-down slow breathing circuit that alleviates negative affect in mice - Nature Neuroscience

www.nature.com/articles/s41593-024-01799-w

積読

Dec 26, 2024

1

Parallel gut-to-brain pathways orchestrate feeding behaviors - Nature Neuroscience

www.nature.com/articles/s41593-024-01828-8

積読

Dec 26, 2024

1