genken

genken

@genken

Hibernation/Hypothalamus/Sympathetic Neuron/PostDoc/movies

Joined Jan 19, 2023

8

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7

Followers

721

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1.30k

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Immobility-associated thromboprotection is conserved across mammalian species from bear to human

www.science.org/doi/10.1126/science.abo5044

hibernation

Jun 11, 2023

65

Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens

www.science.org/doi/10.1126/science.adh7699

Research tool
積読

Jun 11, 2023

21

The Greatest Films of All Time

www.bfi.org.uk/sight-and-sound/greatest-films-all-time

movie
hobby

Jun 11, 2023

Mechanisms of Endocytosis

www.annualreviews.org/doi/10.1146/annurev.biochem.78.081307.110540?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed

Jun 10, 2023

41

www.jstage.jst.go.jp/article/oleoscience/13/10/13_493/_pdf/-char/ja

tau
PLA1A
tau secretion

Jun 9, 2023

ARF6 and Rab11 as intrinsic regulators of axon regeneration

www.tandfonline.com/doi/full/10.1080/21541248.2018.1457914

tau secretion
tau
積読
check up later

Jun 6, 2023

1

Single-cell spatial proteomic imaging for human neuropathology - Acta Neuropathologica Communications

actaneurocomms.biomedcentral.com/articles/10.1186/s40478-022-01465-x

check up later
積読
Research tool

Jun 6, 2023

1

Single-cell spatial proteomic analysis by multiplexed imaging enables identification of microglial heterogeneity in Alzheimer’s disease human brain

www.researchsquare.com/article/rs-2870341/v1

積読
Research tool
spatial proteomics

Jun 6, 2023

1

Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease

onlinelibrary.wiley.com/doi/full/10.1002/ana.26620

積読
tau
tau review
check up later

Jun 6, 2023

11

Commentary: BAG3 as a Mediator of Endosome Function and Tau Clearance

www.sciencedirect.com/science/article/pii/S0306452222002317?via%3Dihub

Jun 1, 2023

61

Abnormal Tau Slips into Synapses Long Before Tangles Form | ALZFORUM

www.alzforum.org/news/research-news/abnormal-tau-slips-synapses-long-tangles-form

tau

Jun 1, 2023

22

Hi-Res Spatial Proteomics Uncovers Aspects of Alzheimer’s Disease Pathology | ALZFORUM

www.alzforum.org/news/research-news/hi-res-spatial-proteomics-uncovers-aspects-alzheimers-disease-pathology

tau
check up later
spatial proteomics
alzheimer disease
Research tool

Jun 1, 2023

52

Dynamic RNA Regulation in the Brain Underlies Physiological Plasticity in a Hibernating Mammal

www.frontiersin.org/articles/10.3389/fphys.2020.624677/full

hibernation
check up later

May 30, 2023

1919

Long-read isoform sequencing reveals tissue-specific isoform expression between active and hibernating brown bears (Ursus arctos)

www.ncbi.nlm.nih.gov/pmc/articles/PMC9210309/

May 30, 2023

11

比較ゲノム配列解析〜冬眠哺乳類で保存性の高い遺伝子群の同定

forum.hibernationbiology.jp/threads/view/9

hibernation

May 30, 2023

11

マウス休眠過程での血中グルコース濃度変化

forum.hibernationbiology.jp/threads/view/3

hibernation

May 30, 2023

3

シリアンハムスター肝細胞の低温耐性に食餌由来のビタミンEが関与する

forum.hibernationbiology.jp/threads/view/1

hibernation
check up later

May 30, 2023

11

ジュウサンセンジリスの夏〜冬〜深冬眠〜中途覚醒〜春の遺伝子発現変化

forum.hibernationbiology.jp/threads/view/6

May 30, 2023

1

Guide to a Postdoc

ubadahsabbagh.com/guide-to-postdoc.php

check up later
career

May 25, 2023

1

Yuki FURUSE 古瀬祐気さんはTwitterを使っています

twitter.com/ykfrs1217/status/1661309276277866496

tool
productivity

May 25, 2023

1

Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation | Proceedings of the National Academy of Sciences

www.pnas.org/doi/10.1073/pnas.2108870119

tau
tau uptake

May 24, 2023

11

Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway

academic.oup.com/brain/article/144/9/2759/6356359?searchresult=1&login=true

tau
tau phosphorylation
AbtoTau

May 24, 2023

22

Syntaxins 6 and 8 facilitate tau into secretory pathways

portlandpress.com/biochemj/article/478/7/1471/228147/Syntaxins-6-and-8-facilitate-tau-into-secretory

tau secretion
tau

May 24, 2023

53

Uncovering tau in wasteosomes (corpora amylacea) of Alzheimer’s disease patients

www.frontiersin.org/articles/10.3389/fnagi.2023.1110425/full

tau

May 24, 2023

22

Clearance of intracellular tau protein from neuronal cells via VAMP8-induced secretion

www.sciencedirect.com/science/article/pii/S0021925817506596?via%3Dihub

tau secretion
tau

May 24, 2023

22

Botulinum neurotoxin A modulates the axonal release of pathological tau in hippocampal neurons

www.sciencedirect.com/science/article/pii/S004101012300096X?via%3Dihub

tau secretion
tau

May 24, 2023

22

Metabotropic Glutamate Receptors Modulate Exocytotic Tau Release and Propagation

jpet.aspetjournals.org/content/383/2/117

tau secretion
tau

May 24, 2023

31

Evolutionary constraint and innovation across hundreds of placental mammals

www.science.org/doi/10.1126/science.abn3943?utm_campaign=SciMag&utm_source=Twitter&utm_medium=ownedSocial

hibernation
check up later

May 24, 2023

87

Seasonal and state-dependent changes in brain TRH receptors in hibernating ground squirrels - PubMed

pubmed.ncbi.nlm.nih.gov/1322229/

hibernation
preoptic area

Apr 12, 2023

11

Arousal following intra-preoptic area administration of naltrexone, ICI 174864 or nor-BNI in hibernating ground squirrels - PubMed

pubmed.ncbi.nlm.nih.gov/8292252/

hibernation
preoptic area

Apr 12, 2023

11

Thyrotropin-releasing hormone induced thermogenesis in Syrian hamsters: site of action and receptor subtype - PubMed

pubmed.ncbi.nlm.nih.gov/15781042/

hibernation
preoptic area

Apr 11, 2023

11

Spatial and temporal activation of brain regions in hibernation: c-fos expression during the hibernation bout in thirteen-lined ground squirrel - PubMed

pubmed.ncbi.nlm.nih.gov/17912746/

hibernation
preoptic area

Apr 11, 2023

11

Changes of characteristics of preoptic neurons and NA metabolism in hypothalamus of ground squirrel (Citelleus Dautieus) in different seasons and hibernating phases - PubMed

pubmed.ncbi.nlm.nih.gov/18726230/

hibernation
preoptic area

Apr 11, 2023

11

Distinct α subunit variations of the hypothalamic GABAA receptor triplets (αβγ) are linked to hibernating state in hamsters - PubMed

pubmed.ncbi.nlm.nih.gov/20815943/

hibernation
preoptic area

Apr 11, 2023

11

CNGA3 acts as a cold sensor in hypothalamic neurons - PubMed

pubmed.ncbi.nlm.nih.gov/32270761/

hibernation
preoptic area

Apr 11, 2023

22

Neurons that regulate mouse torpor - Nature

www.nature.com/articles/s41586-020-2387-5

Mar 22, 2023

11

Quartz-Seq2: a high-throughput single-cell RNA-sequencing method that effectively uses limited sequence reads - Genome Biology

genomebiology.biomedcentral.com/articles/10.1186/s13059-018-1407-3

Mar 22, 2023

1

AI Grammar Checker & Online Academic Writing Tool for Researchers | Paperpal

paperpal.com/

tool

Feb 27, 2023

11

第三の光受容細胞 | Nature ダイジェスト | Nature Portfolio

www.natureasia.com/ja-jp/ndigest/v8/n5/%E7%AC%AC%E4%B8%89%E3%81%AE%E5%85%89%E5%8F%97%E5%AE%B9%E7%B4%B0%E8%83%9E/36521

proposal
hibernation

Feb 15, 2023

21

How does hibernation work? - Sheena Lee Faherty - YouTube

www.youtube.com/watch?v=xptpXSTtgSY

Feb 14, 2023

5

Cellular, Molecular, and Physiological Adaptations of Hibernation: The Solution to Environmental Challenges

www.annualreviews.org/doi/10.1146/annurev-cellbio-012820-095945

Feb 11, 2023

97

Elicitとは?:論文検索AIサイトの使い方と文献検索をわかりやすく紹介 - 化学徒の備忘録(かがろく)|化学系ブログ

www.syero-chem.com/entry/2023/01/25/215047

Feb 10, 2023

11

AI検索エンジン「Perplexity」が調べ物に便利 ユーザーの代わりにWebを検索→簡単に要約して教えてくれる

nlab.itmedia.co.jp/nl/articles/2302/03/news085.html

tool

Feb 10, 2023

11

Rodent brains reveal triggers of hibernation

www.science.org/content/article/rodent-brains-reveal-triggers-hibernation

Feb 10, 2023

2

Staying strong during hibernation

www.science.org/doi/10.1126/science.abn6187

hibernation

Feb 10, 2023

1

Binding characteristics of [18F]PI-2620 distinguish the clinically predicted tau isoform in different tauopathies by PET - PubMed

pubmed.ncbi.nlm.nih.gov/34044665/

check up later
tauPET

Feb 6, 2023

1

Primary Tauopathies Get New PET Ligands | ALZFORUM

www.alzforum.org/news/conference-coverage/primary-tauopathies-get-new-pet-ligands

Jan 27, 2023

1

[18F]RO948 tau positron emission tomography in genetic and sporadic frontotemporal dementia syndromes - PubMed

pubmed.ncbi.nlm.nih.gov/36513817/

tauPET
tau review
RO948

Jan 27, 2023

11

Performance of [18F]RO948 PET, MRI and CSF neurofilament light in the differential diagnosis of progressive supranuclear palsy - PubMed

pubmed.ncbi.nlm.nih.gov/36442367/

RO948
tauPET
tau review

Jan 27, 2023

11