genken

genken

@genken

Hibernation/Hypothalamus/Sympathetic Neuron/PostDoc/movies

Joined Jan 19, 2023

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Updating the striatal–pallidal wiring diagram - Nature Neuroscience

www.nature.com/articles/s41593-023-01518-x

積読
神経回路

Jan 9, 2024

1

A tool kit of highly selective and sensitive genetically encoded neuropeptide sensors

www.science.org/doi/10.1126/science.abq8173

積読
Research tool

Jan 8, 2024

11

Structural visualization of transcription initiation in action

www.science.org/doi/10.1126/science.adi5120

転写

Jan 8, 2024

11

Pregnancy-responsive pools of adult neural stem cells for transient neurogenesis in mothers

www.science.org/doi/10.1126/science.abo5199

積読

Jan 8, 2024

11

Nesting chinstrap penguins accrue large quantities of sleep through seconds-long microsleeps

www.science.org/doi/10.1126/science.adh0771

sleep
積読

Jan 8, 2024

11

Tau in cerebrospinal fluid induces neuronal hyperexcitability and alters hippocampal theta oscillations - Acta Neuropathologica Communications

actaneurocomms.biomedcentral.com/articles/10.1186/s40478-023-01562-5

tau
alzheimer disease

Jan 8, 2024

11

Golgi fragmentation – One of the earliest organelle phenotypes in Alzheimer’s disease neurons

www.frontiersin.org/articles/10.3389/fnins.2023.1120086/full

alzheimer disease
tau

Jan 8, 2024

22

Unconventional secretion of tau by VAMP8 impacts its intra- and extracellular cleavage

www.frontiersin.org/articles/10.3389/fcell.2022.912118/full

tau secretion
tau

Jan 8, 2024

44

Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals

www.cell.com/cell/fulltext/S0092-8674(23)01176-5

積読
読み会候補

Jan 8, 2024

1

APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread

www.cell.com/cell/fulltext/S0092-8674(23)01315-6

積読
alzheimer disease

Jan 8, 2024

11

Stress granules plug and stabilize damaged endolysosomal membranes - Nature

www.nature.com/articles/s41586-023-06726-w

積読
読み会候補

Jan 8, 2024

1

Molecularly defined and spatially resolved cell atlas of the whole mouse brain - Nature

www.nature.com/articles/s41586-023-06808-9

scRNAseq
積読

Jan 8, 2024

1

Brain-wide correspondence of neuronal epigenomics and distant projections - Nature

www.nature.com/articles/s41586-023-06823-w

積読
scRNAseq

Jan 8, 2024

11

Gene expression of single cells mapped in tissue sections

www.nature.com/articles/d41586-023-03788-8

積読
scRNAseq

Jan 8, 2024

11

Conserved and divergent gene regulatory programs of the mammalian neocortex - Nature

www.nature.com/articles/s41586-023-06819-6

積読
evolution

Jan 8, 2024

1

Disease-specific tau filaments assemble via polymorphic intermediates - Nature

www.nature.com/articles/s41586-023-06788-w

alzheimer disease
Alzforum
tau structure

Jan 8, 2024

11

Large-scale cerebrospinal fluid proteomic analysis in Alzheimer’s disease patients reveals five molecular subtypes with distinct genetic risk profiles

www.medrxiv.org/content/10.1101/2023.05.10.23289793v1

Alzforum
alzheimer disease

Jan 8, 2024

11

difference between … of …(正しい)と、difference of … between …(誤用)をきちんと理解する | 或る特許翻訳者の書斎

jiyuugatanookite.com/patent/post-821-821.html

Jan 7, 2024

1

学術英語論文執筆のヒント | Uni-edit.net

www.uni-edit.net/japan/english-writing

英語
文法

Jan 7, 2024

1

【英語論文の書き方】第24回 because, since, as など 理由を表す表現 論文翻訳・英文校正 研究者専門の翻訳会社 ワールド翻訳サービス

www.worldts.com/english-writing/eigo-ronbun24/index.html

Jan 3, 2024

3

【英語文法】Due to と Because of の違い - データ分析メモと北欧生活

keita43a.hatenablog.com/entry/2019/10/09/181606

英語
文法

Jan 3, 2024

4

Endocytosed Cation-Independent Mannose 6-Phosphate Receptor Traffics via the Endocytic Recycling Compartment en Route to the trans-Golgi Network and a Subpopulation of Late Endosomes

www.molbiolcell.org/doi/10.1091/mbc.e03-07-0497

IGF2R

Dec 18, 2023

11

An Effector Domain Mutant of Arf6 Implicates Phospholipase D in Endosomal Membrane Recycling

www.molbiolcell.org/doi/10.1091/mbc.e05-06-0523

Arf6

Dec 16, 2023

33

Neuronal expression of CD22: Novel mechanism for inhibiting microglial proinflammatory cytokine production

onlinelibrary.wiley.com/doi/10.1002/glia.20009

CD22

Dec 12, 2023

11

Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D | Journal of Cell Biology | Rockefeller University Press

rupress.org/jcb/article/196/4/483/36778/Arf6-promotes-autophagosome-formation-via-effects

Arf6
N48RI
Arf6-PLD

Dec 12, 2023

75

The GDP-bound form of Arf6 is located at the plasma membrane

journals.biologists.com/jcs/article/117/11/2389/27697/The-GDP-bound-form-of-Arf6-is-located-at-the

Arf6

Dec 12, 2023

33

CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity

www.frontiersin.org/articles/10.3389/fimmu.2018.02235/full

CD22
積読

Dec 12, 2023

21

Hypersialylation is a common feature of neurofibrillary tangles and granulovacuolar degenerations in Alzheimer's disease and tauopathy brains

onlinelibrary.wiley.com/doi/10.1111/neup.12277

tau
sialylation

Dec 11, 2023

11

CD22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of B cells

www.ncbi.nlm.nih.gov/pmc/articles/PMC3024466/

CD22

Dec 11, 2023

11

Distinct Endocytic Mechanisms of CD22 (Siglec-2) and Siglec-F Reflect Roles in Cell Signaling and Innate Immunity

www.tandfonline.com/doi/full/10.1128/MCB.00383-07

Dec 11, 2023

3

Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity - PubMed

pubmed.ncbi.nlm.nih.gov/17562860/

Dec 11, 2023

Constitutive endocytosis and degradation of CD22 by human B cells - PubMed

pubmed.ncbi.nlm.nih.gov/7722303/

CD22

Dec 11, 2023

1

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

www.cell.com/neuron/fulltext/S0896-6273(13)00316-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627313003164%3Fshowall%3Dtrue

Dec 10, 2023

32

Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration

www.frontiersin.org/articles/10.3389/fncel.2020.00162/full

シアル酸
CD22

Dec 8, 2023

43

GlycoWord / Immunity & Sugar Chain-IS-A06

www.glycoforum.gr.jp/glycoword/immunity/IS-A07J.html

CD22
シアル酸

Dec 8, 2023

63

第 35 話 シアル酸とは  ~シアル酸の構造 | 医化学創薬株式会社

soyaku.co.jp/info/2347/

シアル酸

Dec 8, 2023

11

糖質科学のことば / Glycolipid-A04

www.glycoforum.gr.jp/glycoword/glycolipid/GL-A04J.html

シアル酸

Dec 8, 2023

11

Siglecs in Brain Function and Neurological Disorders

www.mdpi.com/2073-4409/8/10/1125

CD22

Dec 8, 2023

11

CD22 Blockage Restores Age-Related Impairments of Microglia Surveillance Capacity

www.frontiersin.org/articles/10.3389/fimmu.2021.684430/full

CD22

Dec 8, 2023

1512

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains - Nature

www.nature.com/articles/s41586-019-1088-4

CD22

Dec 8, 2023

117

Distinct tau folds initiate templated seeding and alter the post-translational modification profile

academic.oup.com/brain/advance-article/doi/10.1093/brain/awad272/7240187?login=true

alzheimer disease
tau phosphorylation
tau structure
tau

Nov 29, 2023

86

FEBS Press

febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13657

tau
tau structure
alzheimer disease

Nov 29, 2023

11

CARD9 attenuates Aβ pathology and modifies microglial responses in an Alzheimer’s disease mouse model | Proceedings of the National Academy of Sciences

www.pnas.org/doi/full/10.1073/pnas.2303760120

CD22

Nov 23, 2023

33

PTEN deficiency exposes a requirement for an ARF GTPase module for integrin‐dependent invasion in ovarian cancer

www.embopress.org/doi/full/10.15252/embj.2023113987

積読
Arf6

Nov 22, 2023

11

The ARF GTPase regulatory network in collective invasion and metastasis

portlandpress.com/biochemsoctrans/article/51/4/1559/233421/The-ARF-GTPase-regulatory-network-in-collective

Arf6

Nov 22, 2023

54

Identification of phosphorylated tau protein interactors in progressive supranuclear palsy (PSP) reveals networks involved in protein degradation, stress response, cytoskeletal dynamics, metabolic processes, and neurotransmission

onlinelibrary.wiley.com/doi/10.1111/jnc.15796

tau
Arf6

Nov 22, 2023

22

シングルセル解析③:ダブレット推定手法について - Aurora blog

auroratummy.hatenablog.com/entry/2020/10/28/072113

scRNAseq

Nov 21, 2023

11

Hygromycin B Gold | Selection Antibiotic | InvivoGen

www.invivogen.com/hygromycin

Research tool

Nov 21, 2023

1