genken

genken

@genken

Hibernation/Hypothalamus/Sympathetic Neuron/PostDoc/movies

Joined Jan 19, 2023

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721

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Identification and Importance of Brown Adipose Tissue in Adult Humans | NEJM

www.nejm.org/doi/full/10.1056/NEJMoa0810780

BAT
brown adipose tissue
積読

Jan 3, 2026

1

Comprehensive quantification of metabolic flux during acute cold stress in mice - PubMed

pubmed.ncbi.nlm.nih.gov/37802078/

Dec 30, 2025

1

Cold-sensitive ventromedial hypothalamic neurons control homeostatic thermogenesis and social interaction-associated hyperthermia - PubMed

pubmed.ncbi.nlm.nih.gov/35675799/

thermogenesis
積読

Dec 30, 2025

1

Regulation of Body Temperature by the Nervous System

www.cell.com/neuron/fulltext/S0896-6273(18)30143-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627318301430%3Fshowall%3Dtrue

Dec 15, 2025

1

Sensory input, sex and function shape hypothalamic cell type development - Nature

www.nature.com/articles/s41586-025-08603-0

Research tool
scRNAseq

Dec 5, 2025

1

in situ hybridizationの簡易プロトコール - ノンコーディングRNAネオタクソノミ

ncrna.jp/super-resolution/tips/item/75-in-situ-hybridization

protocol

Dec 2, 2025

1

Binary Switching of Calendar Cells in the Pituitary Defines the Phase of the Circannual Cycle in Mammals

www.sciencedirect.com/science/article/pii/S0960982215010933?via%3Dihub

hibernation

Nov 27, 2025

Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury

www.sciencedirect.com/science/article/pii/S0896627320308230?via%3Dihub

Nov 10, 2025

1

Kappa opioids inhibit spinal output neurons to suppress itch

www.science.org/doi/10.1126/sciadv.adp6038

itch
spinal cord
JC

Nov 8, 2025

5

Central circuit mechanisms of itch - Nature Communications

www.nature.com/articles/s41467-020-16859-5

itch
spinal cord

Nov 7, 2025

1

Synaptic control of spinal GRPR+ neurons by local and long-range inhibitory inputs | PNAS

www.pnas.org/doi/10.1073/pnas.1905658116?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed

spinal cord

Nov 6, 2025

1

A neuropeptide code for itch - Nature Reviews Neuroscience

www.nature.com/articles/s41583-021-00526-9

itch
spinal cord

Nov 6, 2025

81

A Functional Topographic Map for Spinal Sensorimotor Reflexes

www.sciencedirect.com/science/article/pii/S0896627320307716?via%3Dihub

itc
spinal cord

Nov 6, 2025

98

Grpr expression defines a population of superficial dorsal... : PAIN

journals.lww.com/pain/fulltext/2023/01000/grpr_expression_defines_a_population_of.21.aspx

itch
spinal cord

Nov 6, 2025

88

Neuropeptide Y neurons mediate opioid-induced itch by disinhibiting GRP-GRPR microcircuits in the spinal cord - Nature Communications

www.nature.com/articles/s41467-025-62382-w?fromPaywallRec=false

itch
spinal cord
JC

Nov 5, 2025

1

Kappa opioids inhibit spinal output neurons to suppress itch

www.science.org/doi/10.1126/sciadv.adp6038?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

itch
spinal cord
JC

Nov 5, 2025

1

Gate control of mechanical itch by a subpopulation of spinal cord interneurons

www.science.org/doi/10.1126/science.aac8653

spinal cord
itch

Nov 5, 2025

11

A central neural circuit for itch sensation

www.science.org/doi/10.1126/science.aaf4918

spinal cord
itch
JC

Nov 5, 2025

32

Neural circuits for pain: Recent advances and current views

www.science.org/doi/10.1126/science.aaf8933

spinal cord
sensory neuron
JC

Nov 5, 2025

33

Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression - Genome Biology

genomebiology.biomedcentral.com/articles/10.1186/s13059-019-1874-1

scRNAseq
SCTransform

Oct 22, 2025

117

Negative Binomial Regression | R Data Analysis Examples

stats.oarc.ucla.edu/r/dae/negative-binomial-regression/

Oct 22, 2025

Using sctransform in Seurat

satijalab.org/seurat/articles/sctransform_vignette.html

Research tool

Oct 22, 2025

1

Genetic loci associated with heart rate variability and their effects on cardiac disease risk - Nature Communications

www.nature.com/articles/ncomms15805

自律神経失調症

Oct 19, 2025

1

Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system - Nature Communications

www.nature.com/articles/s41467-018-04148-1

自律神経失調症

Oct 19, 2025

1

Genetic study links components of the autonomous nervous system to heart-rate profile during exercise - Nature Communications

www.nature.com/articles/s41467-018-03395-6

自律神経失調症
spinal cord

Oct 19, 2025

1

Optimizing Xenium In Situ data utility by quality assessment and best-practice analysis workflows - Nature Methods

www.nature.com/articles/s41592-025-02617-2

spatial TC
tool
best practices
Xenium

Oct 19, 2025

1

東京大学・新領域 北川研究室

kitagawa-lab.jp/works

Oct 18, 2025

11

High resolution mapping of the tumor microenvironment using integrated single-cell, spatial and in situ analysis - Nature Communications

www.nature.com/articles/s41467-023-43458-x

Xenium
scRNAseq
spatial TC

Oct 12, 2025

1

Single Cell Pathway Analysis

jackbibby1.github.io/SCPA/

scRNAseq
tool

Oct 12, 2025

1

Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition

www.cell.com/cell-reports/fulltext/S2211-1247(24)01227-0

spinal cord
spatial TC
scRNAseq

Sep 23, 2025

1

SpineRacks and SpinalJ for efficient analysis of neurons in a 3D reference atlas of the mouse spinal cord

star-protocols.cell.com/protocols/1177

spinal cord
SpinalJ
dry tool

Sep 17, 2025

1

PACAP mRNA is expressed in rat spinal cord neurons

onlinelibrary.wiley.com/doi/10.1002/cne.20015

PACAP
in situ hybridization

Sep 15, 2025

1

Pituitary adenylate cyclase‐activating peptide in the rat central nervous system: An immunohistochemical and in situ hybridization study

onlinelibrary.wiley.com/doi/full/10.1002/cne.10418?sid=nlm%3Apubmed

PACAP
in situ hybridization

Sep 15, 2025

2

Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types - Nature Neuroscience

www.nature.com/articles/s41593-018-0141-1

spinal cord
resource
scRNAseq

Sep 12, 2025

Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior

www.sciencedirect.com/science/article/pii/S221112471830158X?via%3Dihub

scRNAseq
spinal cord
resource

Sep 12, 2025

Estrogens influence female itch sensitivity via the spinal gastrin-releasing peptide receptor neurons | PNAS

www.pnas.org/doi/10.1073/pnas.2103536118

itch
sensory neuron

Sep 9, 2025

Mouse Models of Itch

www.sciencedirect.com/science/article/pii/S0022202X24020876?via%3Dihub

itch

Sep 9, 2025

An inter-organ neural circuit for appetite suppression

www.sciencedirect.com/science/article/pii/S0092867422005918?via%3Dihub

inter-organ
Cell
sympathetic nervous system

Sep 9, 2025

Transplanted Human Stem Cell-Derived Interneuron Precursors Mitigate Mouse Bladder Dysfunction and Central Neuropathic Pain after Spinal Cord Injury

www.cell.com/cell-stem-cell/fulltext/S1934-5909(16)30267-3

bladder
spinal cord

Sep 2, 2025

Organization of lumbar spinal outflow to distal colon and pelvic organs | Physiological Reviews | American Physiological Society

journals.physiology.org/doi/abs/10.1152/physrev.1987.67.4.1332

lumbar
交感神経
自律神経
自律神経

Aug 27, 2025

ニットーボーメディカル株式会社 -4.新規固定剤グリオキサールの威力

nittobo-nmd.co.jp/column/column-04.html

Crh
fixation

Aug 24, 2025

説明ページ

www.kyorin-u.ac.jp/univ/user/health/pathology/e-learning/setumei01/HCONT02/s0005_2.html

Crh
Crh
fixation

Aug 24, 2025

中央水産研究所

nrifs.fra.affrc.go.jp/news/news25/2502-1.html

CRH neurons
Crh
IHC
fixation

Aug 24, 2025

Spinal projections of the A5, A6 (locus coeruleus), and A7 noradrenergic cell groups in rats

onlinelibrary.wiley.com/doi/10.1002/cne.23024

sympathetic nervous system

Aug 16, 2025

Mechanisms for pituitary adenylate cyclase-activating polypeptide-induced increase in excitability in guinea-pig and mouse adrenal medullary cells

www.sciencedirect.com/science/article/pii/S0014299920300480?via%3Dihub

PACAP
sympathetic nervous system
交感神経

Aug 13, 2025

Spinal origins of preganglionic B and C neurons that innervate paravertebral sympathetic ganglia nine and ten of the bullfrog

onlinelibrary.wiley.com/doi/abs/10.1002/cne.902680108?sid=nlm%3Apubmed

sympathetic nervous system
自律神経

Aug 12, 2025

Neurally released pituitary adenylate cyclase‐activating polypeptide enhances guinea pig intrinsic cardiac neurone excitability

physoc.onlinelibrary.wiley.com/doi/10.1113/jphysiol.2007.134965

sympathetic nervous system
交感神経
PACAP

Aug 12, 2025

An atlas of brain-bone sympathetic neural circuits in mice

elifesciences.org/articles/95727

交感神経
sympathetic nervous system

Aug 9, 2025

The sacral autonomic outflow is sympathetic

www.science.org/doi/10.1126/science.aah5454

sympathetic nervous system
自律神経

Aug 5, 2025

Genomic convergence in hibernating mammals elucidates the genetics of metabolic regulation in the hypothalamus

www.science.org/doi/10.1126/science.adp4025

hibernation
hypothalamus
scRNAseq

Aug 1, 2025