genken

genken

@genken

Hibernation/Hypothalamus/Sympathetic Neuron/PostDoc/movies

Joined Jan 19, 2023

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721

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DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon | Journal of Cell Biology | Rockefeller University Press

rupress.org/jcb/article/216/11/3625/38999/DC2-and-KCP2-mediate-the-interaction-between-the

KCP2

Sep 12, 2023

1

Keratinocyte-associated protein 2 is a bona fide subunit of the mammalian oligosaccharyltransferase

journals.biologists.com/jcs/article/125/1/220/32259/Keratinocyte-associated-protein-2-is-a-bona-fide

KCP2

Sep 12, 2023

1

A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells - Nature Communications

www.nature.com/articles/s41467-021-23274-x

読み会

Sep 1, 2023

2

LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits - Nature Aging

www.nature.com/articles/s43587-023-00464-4

読み会

Aug 25, 2023

33

Formation of Disulfide Bridges Drives Oligomerization, Membrane Pore Formation, and Translocation of Fibroblast Growth Factor 2 to Cell Surfaces

www.sciencedirect.com/science/article/pii/S0021925819819865

FGF2
tau secretion

Aug 21, 2023

11

Distinct spatial maps and multiple object codes in the lateral entorhinal cortex

www.sciencedirect.com/science/article/pii/S0896627323004798

Aug 17, 2023

88

www.cell.com/neuron/pdf/S0896-6273(23)00479-8.pdf

JC

Aug 17, 2023

WNT5A - Protein Wnt-5a - Homo sapiens (Human) | UniProtKB | UniProt

www.uniprot.org/uniprotkb/P41221/entry

Aug 10, 2023

TRIM11 protects against tauopathies and is down-regulated in Alzheimer’s disease

www.science.org/doi/10.1126/science.add6696

JC
tau

Aug 3, 2023

1

Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist | Proceedings of the National Academy of Sciences

www.pnas.org/doi/10.1073/pnas.2014879117

JC

Jul 27, 2023

1

Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer’s disease - Nature Communications

www.nature.com/articles/s41467-023-37316-z

読み会
alzheimer disease

Jul 21, 2023

1

Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area

www.sciencedirect.com/science/article/pii/S0896627319303927

積読
preoptic area
thermoregulation

Jul 20, 2023

1

Warm-Sensitive Neurons that Control Body Temperature

www.cell.com/fulltext/S0092-8674(16)31079-0

preoptic area
thermoregulation
hypothalamus

Jul 19, 2023

1

Seasonal decrease in thermogenesis and increase in vasoconstriction explain seasonal response to N6‐cyclohexyladenosine‐induced hibernation in the Arctic ground squirrel (Urocitellus parryii)

onlinelibrary.wiley.com/doi/10.1111/jnc.14814

hibernation
cFos

Jul 19, 2023

97

Clock Gene Expression in the Suprachiasmatic Nucleus of Hibernating Arctic Ground Squirrels - Tomoko Ikeno, Cory T. Williams, C. Loren Buck, Brian M. Barnes, Lily Yan, 2017

journals.sagepub.com/doi/10.1177/0748730417702246?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

hibernation
SCN
cFos

Jul 19, 2023

54

Neuronal Activity in the Hibernating Brain

www.frontiersin.org/articles/10.3389/fnana.2019.00071/full

積読
hibernation

Jul 18, 2023

1311

Gene Expression in the Brain across the Hibernation Cycle

www.jneurosci.org/content/19/10/3781/tab-figures-data

hibernation

Jul 18, 2023

Berlin-Hamster-Single-Cell-Consortium · GitHub

github.com/Berlin-Hamster-Single-Cell-Consortium

hamster
scRNAseq

Jul 18, 2023

11

Spatial and temporal activation of brain regions in hibernation: c‐fos expression during the hibernation bout in thirteen‐lined ground squirrel

onlinelibrary.wiley.com/doi/10.1002/cne.21507

hibernation
preoptic area
cFos

Jul 18, 2023

C-fos mRNA increases in the ground squirrel suprachiasmatic nucleus during arousal from hibernation

www.sciencedirect.com/science/article/pii/0304394094907234?via%3Dihub

hibernation
cFos

Jul 18, 2023

11

Hypothalamic orexinergic neuron changes during the hibernation of the Syrian hamster

www.frontiersin.org/articles/10.3389/fnana.2022.993421/full

hibernation
cFos

Jul 18, 2023

98

Gene Expression in the Brain across the Hibernation Cycle

www.jneurosci.org/content/19/10/3781.long

hibernation
cFos

Jul 18, 2023

33

Tau Propagation Surprise: It Might Travel Retrogradely | ALZFORUM

www.alzforum.org/news/research-news/tau-propagation-surprise-it-might-travel-retrogradely

積読
tau
Alzforum

Jul 17, 2023

33

Parallel Accelerated Evolution in Distant Hibernators Reveals Candidate Cis Elements and Genetic Circuits Regulating Mammalian Obesity

www.cell.com/cell-reports/fulltext/S2211-1247(19)31435-4

hibernation
冬眠研究の意義

Jul 12, 2023

1

How hibernation and hypothermia help to improve anticoagulant control

www.tandfonline.com/doi/full/10.4161/23328940.2014.967595

hibernation
冬眠研究の意義

Jul 12, 2023

1

plaza.umin.ac.jp/~beehappy/analgesia/method-ani-ephysi.html

Jul 9, 2023

1

APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge

www.sciencedirect.com/science/article/pii/S2211124723002073?via%3Dihub

読み会

Jul 7, 2023

11

A mosaic of new and old cell types

www.science.org/doi/10.1126/science.add9465

積読

Jul 7, 2023

11

Genetic Dissection of Neural Circuits: A Decade of Progress

www.cell.com/neuron/fulltext/S0896-6273(18)30246-0

積読

Jul 7, 2023

1

EASI-FISH for thick tissue defines lateral hypothalamus spatio-molecular organization

www.cell.com/cell/fulltext/S0092-8674(21)01339-8

hypothalamus
LHA

Jul 7, 2023

1

Circuit coordination of opposing neuropeptide and neurotransmitter signals - Nature

www.nature.com/articles/s41586-023-06246-7

積読

Jul 7, 2023

1

Glymphatic influx and clearance are accelerated by neurovascular coupling - Nature Neuroscience

www.nature.com/articles/s41593-023-01327-2

積読
Glymphatic system

Jul 7, 2023

1

Spatially resolved single-cell translatomics at molecular resolution

www.science.org/doi/10.1126/science.add3067

積読
Research tool

Jul 7, 2023

1

Early Alzheimer’s disease pathology in human cortex is associated with a transient phase of distinct cell states

www.biorxiv.org/content/10.1101/2023.06.03.543569v1.full

積読
alzheimer disease

Jul 7, 2023

1

Dynamic mapping of proteome trafficking within and between living cells by TransitID

www.cell.com/cell/fulltext/S0092-8674(23)00596-2

Jul 4, 2023

1

β-Amyloid (D54D2) XP® Rabbit mAb

www.cellsignal.jp/products/primary-antibodies/b-amyloid-d54d2-xp-rabbit-mab/8243

seminar
Ab

Jul 3, 2023

11

A kidney-brain neural circuit drives progressive kidney damage and heart failure - Signal Transduction and Targeted Therapy

www.nature.com/articles/s41392-023-01402-x

積読
Research tool
synapse tracer
JC

Jun 29, 2023

1

Sleep sculpts circuits in every species studied

www.cell.com/cell/fulltext/S0092-8674(23)00594-9

積読

Jun 27, 2023

1

Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients

www.science.org/doi/10.1126/scitranslmed.aam7621?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

読み会

Jun 23, 2023

53

Current Knowledge on Mammalian Phospholipase A1, Brief History, Structures, Biochemical and Pathophysiological Roles

www.mdpi.com/1420-3049/27/8/2487

PLA1A

Jun 20, 2023

22

The activation loop of PIP5K functions as a membrane sensor essential for lipid substrate processing

www.science.org/doi/10.1126/sciadv.1600925

PIP5K

Jun 20, 2023

11

Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis

www.mdpi.com/1422-0067/22/23/12685

PLA1A

Jun 19, 2023

11

PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria

www.ncbi.nlm.nih.gov/pmc/articles/PMC6757148/

PLA1A

Jun 19, 2023

11

阻害剤調製時に知っておきたい5つのポイント | M-hub(エムハブ)

m-hub.jp/biology/2683/176

Research tool

Jun 19, 2023

1

ARF6 regulates a plasma membrane pool of phosphatidylinositol(4,5)bisphosphate required for regulated exocytosis

rupress.org/jcb/article-standard/162/4/647/33350/ARF6-regulates-a-plasma-membrane-pool-of

Jun 17, 2023

54

Annexin V Assay Kits | MBLライフサイエンス

ruo.mbl.co.jp/bio/product/apoptosis/annexin.html

Jun 17, 2023

11

Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice

www.embopress.org/doi/full/10.15252/embr.202050219

Jun 16, 2023

1

Antiviral mechanism of preclinical antimalarial compounds possessing multiple antiviral activities

www.ncbi.nlm.nih.gov/pmc/articles/PMC8103717/

PLA1A

Jun 16, 2023

11

PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria

karger.com/jin/article/10/4/315/180107/PLA1A-Participates-in-the-Antiviral-Innate-Immune

PLA1A
knockdown

Jun 16, 2023

21

Chlorate: A reversible inhibitor of proteoglycan sulfation

www.sciencedirect.com/science/article/pii/0006291X88906948

Jun 15, 2023

11