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Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans - Scientific Reports

www.nature.com/articles/s41598-019-51608-9

Jan 27, 2025

1

Release and elimination of dopamine in vivo in mice lacking the dopamine transporter: functional consequences

onlinelibrary.wiley.com/doi/abs/10.1046/j.1460-9568.2000.00155.x?casa_token=3kCmOZ1Rf1gAAAAA%3APgXqhDV_VbI8EHJtbypOaqbAmlgTa5fwGO5aiQdN50VMQE_ELVEbGo-z8B2lO7RGxFLeHBJJrtRZTQWs

Jan 27, 2025

6

Identification of the redox-stress signaling threshold (RST): Increased RST helps to delay aging in C. elegans - PubMed

pubmed.ncbi.nlm.nih.gov/34843919/

Jan 27, 2025

3

A Necessary Role for PKC-2 and TPA-1 in Olfactory Memory and Synaptic AMPAR Trafficking in Caenorhabditis elegans

www.jneurosci.org/content/44/10/e1120232024

Jan 27, 2025

5

Textpresso Central

www.alliancegenome.org/textpresso/wb/tpc/search

Jan 27, 2025

12

Cocaine Modulates Locomotion Behavior in C. elegans

journals.plos.org/plosone/article?id=10.1371/journal.pone.0005946

Jan 27, 2025

13

The Treadmill Exercise Protects against Dopaminergic Neuron Loss and Brain Oxidative Stress in Parkinsonian Rats - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC5497606/

Jan 27, 2025

4

Exercise-Induced Neuroprotection of the Nigrostriatal Dopamine System in Parkinson's Disease - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC5675869/

Jan 27, 2025

2

Meta‐analysis of early nonmotor features and risk factors for Parkinson disease

onlinelibrary-wiley-com.ezpv7-web-p-u01.wpi.edu/doi/full/10.1002/ana.23687

Jan 27, 2025

2

Frontiers | Recent Advances in Biomarkers for Parkinson’s Disease

www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2018.00305/full

Jan 27, 2025

3

SLC6A3 gene: MedlinePlus Genetics

medlineplus.gov/genetics/gene/slc6a3/

Jan 27, 2025

2

Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC2597780/

Jan 27, 2025

7

In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease

onlinelibrary-wiley-com.ezpv7-web-p-u01.wpi.edu/doi/abs/10.1002/1531-8249(200004)47:4%3C493::AID-ANA13%3E3.0.CO;2-4

Jan 27, 2025

2

Dynamic control of the dopamine transporter in neurotransmission and homeostasis - npj Parkinson's Disease

www.nature.com/articles/s41531-021-00161-2

Jan 27, 2025

1

Vigorous Motor Activity in Caenorhabditis elegans Requires Efficient Clearance of Dopamine Mediated by Synaptic Localization of the Dopamine Transporter DAT-1 - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC6673513/

Jan 27, 2025

1

An unbiased, automated platform for scoring dopaminergic neurodegeneration in C. elegans

journals.plos.org/plosone/article?id=10.1371/journal.pone.0281797

Jan 27, 2025

40

Morphological hallmarks of dopaminergic neurodegeneration are associated with altered neuron function in Caenorhabditis elegans

www.sciencedirect.com/science/article/pii/S0161813X23001523

Jan 27, 2025

3

Mitochondria and calcium signaling

www.sciencedirect.com/science/article/pii/S0143416005000965

Jan 27, 2025

9

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α‐synuclein

onlinelibrary-wiley-com.ezpv7-web-p-u01.wpi.edu/doi/full/10.1046/j.1471-4159.2003.01809.x

Jan 27, 2025

181

Familial Parkinson Mutant α-Synuclein Causes Dopamine Neuron Dysfunction in Transgenic Caenorhabditis elegans

www.sciencedirect.com/science/article/pii/S0021925819478083?via%3Dihub

Jan 27, 2025

30

Extracellular Dopamine Potentiates Mn-Induced Oxidative Stress, Lifespan Reduction, and Dopaminergic Neurodegeneration in a BLI-3–Dependent Manner in Caenorhabditis elegans - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC2928785/

Jan 27, 2025

2

Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC4480853/

Jan 27, 2025

7

NCoR1 is a conserved physiological modulator of muscle mass and oxidative function - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC3225739/

Jan 27, 2025

1

A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC5040492/

Jan 27, 2025

2

The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans | PNAS

www.pnas.org/doi/full/10.1073/pnas.152161099

Jan 27, 2025

2

NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function

www.cell.com/cell/fulltext/S0092-8674(11)01223-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867411012232%3Fshowall%3Dtrue

Jan 27, 2025

1

Ward A et al. (2009) PLoS One "Cocaine modulates locomotion behavior in C. elegans." (paper) - WormBase : Nematode Information Resource

wormbase.org/resources/paper/WBPaper00034643

Jan 27, 2025

2

Kow, R.L. et al. (2019) International Worm Meeting "Loss of bas-1 suppresses tau-induced toxicity in a Caenorhabditis elegans model of tau toxicity via kinases and phosphatases." (paper) - WormBase : Nematode Information Resource

wormbase.org/resources/paper/WBPaper00058451

Jan 27, 2025

2

Disruption of mitochondrial dynamics affects behaviour and lifespan in Caenorhabditis elegans - Cellular and Molecular Life Sciences

link.springer.com/article/10.1007/s00018-019-03024-5

Jan 27, 2025

1

Neurotransmitter signaling through heterotrimeric G proteins: insights from studies in C. elegans

www.wormbook.org/chapters/www_heterotrimericGproteins.2/neurotransGprotein.html

Jan 27, 2025

10

Methods for Modulating and Measuring Neuromuscular Exertion in C. elegans

link.springer.com/protocol/10.1007/978-1-0716-2181-3_19

Jan 27, 2025

4

Spatial and temporal scales of dopamine transmission - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC8220193/

Jan 27, 2025

3

Mechanisms and regulation of dopamine release - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC6629510/

Jan 27, 2025

3

Neuron matters: electric activation of neuronal tissue is dependent on the interaction between the neuron and the electric field - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC4534030/

Jan 26, 2025

1

Calcium activation of cortical neurons by continuous electrical stimulation: Frequency-dependence, temporal fidelity and activation density - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC6469875/

Jan 26, 2025

4

Amplitude- and frequency-dependent activation of layer II/III neurons by intracortical microstimulation - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC10616374/

Jan 26, 2025

2

Alpha-linolenic acid suppresses dopaminergic neurodegeneration induced by 6-OHDA in C. elegans

www.sciencedirect.com/science/article/pii/S0031938415300792?via%3Dihub

Jan 26, 2025

1

Exercise preserves physical fitness during aging through AMPK and mitochondrial dynamics - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC9926278/

Jan 22, 2025

6

A worm’s life: AMPK links muscle mitochondrial dynamics to physical fitness and healthy aging in Caenorhabditis elegans - PMC

pmc.ncbi.nlm.nih.gov/articles/PMC10256235/

Jan 22, 2025

2

Download Our Stainless Steel Hypodermic Tubing Gage Chart | New England Small Tube

nesmalltube.com/about_tubing/hypodermic.html

Jan 15, 2025

1

0

Extracellular Dopamine Potentiates Mn-Induced Oxidative Stress, Lifespan Reduction, and Dopaminergic Neurodegeneration in a BLI-3–Dependent Manner in Caenorhabditis elegans - PMC

URL
https://pmc.ncbi.nlm.nih.gov/articles/PMC2928785/

Highlights & Notes

Combining genetics and biochemical assays, we established that extracellular, and not intracellular, dopamine (DA) is responsible for Mn-induced DAergic neurodegeneration and that this process (1) requires functional DA-reuptake transporter (DAT-1) and (2) is associated with oxidative stress and lifespan reduction

These results suggest that in vivo BLI-3 activity promotes the conversion of extracellular DA into toxic reactive species, which, in turn, can be taken up by DAT-1 in DAergic neurons, thus leading to oxidative stress and cell degeneration.