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Caleb Han

Caleb Han

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Joined Aug 11, 2022

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Posts

Neurodegeneration in Multiple Sclerosis: Symptoms of Silent Progression, Biomarkers and Neuroprotective Therapy—Kynurenines Are Important Players

www.ncbi.nlm.nih.gov/pmc/articles/PMC8201043/

Aug 16, 2024

1

The pathogenesis of multiple sclerosis: a series of unfortunate events

academic.oup.com/cei/article/214/1/1/7220658

Aug 16, 2024

2

CC Chemokine Receptor 8 in the Central Nervous System Is Associated with Phagocytic Macrophages

www.ncbi.nlm.nih.gov/pmc/articles/PMC1851139/

Aug 15, 2024

2

TLR4-RelA-miR-30a signal pathway regulates Th17 differentiation during experimental autoimmune encephalomyelitis development - Journal of Neuroinflammation

jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-019-1579-0

Aug 14, 2024

2

Critical role of antigen-specific antibody in experimental autoimmune encephalomyelitis induced by recombinant myelin oligodendrocyte glycoprotein - PubMed

pubmed.ncbi.nlm.nih.gov/12115610/

Aug 9, 2024

3

Unique B cell responses in B cell-dependent and B cell-independent EAE

www.tandfonline.com/doi/full/10.3109/08916934.2011.616558

Aug 9, 2024

4

CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis

www.ncbi.nlm.nih.gov/pmc/articles/PMC4001543/

Aug 2, 2024

4

CCR5 knockout suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice

www.ncbi.nlm.nih.gov/pmc/articles/PMC4941248/

Aug 1, 2024

2

Primer-Blast results

www.ncbi.nlm.nih.gov/tools/primer-blast/primertool.cgi?ctg_time=1721892437&job_key=fnSgw_be-3bcTGtJZilPexwyXkkxIUVUMA

Jul 31, 2024

IL-23 stabilizes an effector Treg cell program in the tumor microenvironment - Nature Immunology

www.nature.com/articles/s41590-024-01755-7

Jul 17, 2024

1

Single-Cell Analysis Reveals the Range of Transcriptional States of Circulating Human Neutrophils

journals.aai.org/jimmunol/article/209/4/772/234261/Single-Cell-Analysis-Reveals-the-Range-of

Jul 16, 2024

5

Distinct transcription factor networks control neutrophil-driven inflammation - Nature Immunology

www.nature.com/articles/s41590-021-00968-4

Jul 16, 2024

1

Neutrophil-lymphocyte ratio as a marker for disability and activity in multiple sclerosis

www.sciencedirect.com/science/article/pii/S2211034821001887

Jun 27, 2024

1

Frontiers | Sustained Infiltration of Neutrophils Into the CNS Results in Increased Demyelination in a Viral-Induced Model of Multiple Sclerosis

www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.931388/full

Jun 27, 2024

1

The role of B cells in Multiple Sclerosis and related disorders

www.ncbi.nlm.nih.gov/pmc/articles/PMC8007167/

Jun 3, 2024

5

Neuroantigen-Specific CD8+ Regulatory T-Cell Function is Deficient During Acute Exacerbation of Multiple Sclerosis

www.ncbi.nlm.nih.gov/pmc/articles/PMC3046327/

Jun 3, 2024

2

Neuroantigen-specific CD8+ regulatory T-cell function is deficient during acute exacerbation of multiple sclerosis - PubMed

pubmed.ncbi.nlm.nih.gov/21257291/

Jun 3, 2024

2

The immunology of multiple sclerosis - Nature Reviews Immunology

www.nature.com/articles/s41577-022-00718-z

Jun 3, 2024

419

Cross-reactive EBNA1 immunity targets alpha-crystallin B and is associated with multiple sclerosis

www.science.org/doi/10.1126/sciadv.adg3032?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

Jun 3, 2024

14

The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis

www.ncbi.nlm.nih.gov/pmc/articles/PMC10236715/

May 30, 2024

1

Th2 cytokines and asthma — The role of interleukin-5 in allergic eosinophilic disease

www.ncbi.nlm.nih.gov/pmc/articles/PMC59571/

May 30, 2024

2

Murine IgG1 Complexes Trigger Immune Effector Functions Predominantly via FcγRIII (CD16)1

journals.aai.org/jimmunol/article/161/6/3026/31432/Murine-IgG1-Complexes-Trigger-Immune-Effector

May 30, 2024

1

Characterization of Mannose Receptor-Dependent Phagocytosis Mediated by Mycobacterium tuberculosis Lipoarabinomannan

www.ncbi.nlm.nih.gov/pmc/articles/PMC108268/

May 30, 2024

1

From thymus to tissues and tumors: A review of T-cell biology

www.sciencedirect.com/science/article/pii/S0091674922013781

May 29, 2024

17

Antigen presentation by dendritic cells and their instruction of CD4+ T helper cell responses

www.ncbi.nlm.nih.gov/pmc/articles/PMC7264306/

May 29, 2024

622

Mannose receptor-mediated uptake of antigens strongly enhances HLA class II-restricted antigen presentation by cultured dendritic cells - PubMed

pubmed.ncbi.nlm.nih.gov/9341789/

May 28, 2024

1

Th1 and Th2 cytokines cooperate to stimulate mannose-receptor-mediated phagocytosis - PubMed

pubmed.ncbi.nlm.nih.gov/9665284/

May 28, 2024

3

Distinct integrin activation pathways for effector and regulatory T cell trafficking and function | Journal of Experimental Medicine | Rockefeller University Press

rupress.org/jem/article/218/2/e20201524/211498/Distinct-integrin-activation-pathways-for-effector

May 27, 2024

1

Targeting leukocyte integrins in human diseases

academic.oup.com/jleukbio/article/77/2/129/6845328?login=true

May 27, 2024

2

A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity

www.sciencedirect.com/science/article/pii/S1074761311002597?via%3Dihub

May 23, 2024

8

A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity - PubMed

pubmed.ncbi.nlm.nih.gov/21723159/

May 23, 2024

4

Generation and Function of Induced Regulatory T Cells

www.ncbi.nlm.nih.gov/pmc/articles/PMC3685796/

May 23, 2024

4

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate - PubMed

pubmed.ncbi.nlm.nih.gov/20072126/

May 23, 2024

3

Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells

www.sciencedirect.com/science/article/pii/S1074761321001679?via%3Dihub

May 23, 2024

2

Foxp3 Instability Helps tTregs Distinguish Self and Non-self

www.ncbi.nlm.nih.gov/pmc/articles/PMC6769115/

May 23, 2024

1

Autocrine TGF-β1 Maintains the Stability of Foxp3+ Regulatory T Cells via IL-12Rβ2 Downregulation

www.ncbi.nlm.nih.gov/pmc/articles/PMC7356964/

May 23, 2024

1

Peripherally Induced Tregs – Role in Immune Homeostasis and Autoimmunity

www.ncbi.nlm.nih.gov/pmc/articles/PMC3736167/

May 23, 2024

16

T-Cell Tolerance: Central and Peripheral

www.ncbi.nlm.nih.gov/pmc/articles/PMC3367546/

May 23, 2024

2

Intricacies of TGF-β signaling in Treg and Th17 cell biology - Cellular & Molecular Immunology

www.nature.com/articles/s41423-023-01036-7

May 22, 2024

45

Frontiers | Emerging Functions of Regulatory T Cells in Tissue Homeostasis

www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.00883/full

May 22, 2024

10

Regulatory T Cell Heterogeneity in the Thymus: Impact on Their Functional Activities

www.ncbi.nlm.nih.gov/pmc/articles/PMC7904894/

May 22, 2024

16

Distinct roles of ICOS and CD40L in human T-B cell adhesion and antibody production

www.sciencedirect.com/science/article/pii/S0008874921001398

May 22, 2024

2

T follicular helper cell differentiation, function, and roles in disease

www.ncbi.nlm.nih.gov/pmc/articles/PMC4223692/

May 22, 2024

26

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

www.sciencedirect.com/science/article/pii/S0092867418307232

May 21, 2024

1

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

www.ncbi.nlm.nih.gov/pmc/articles/PMC3229753/

May 20, 2024

3

Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: a comparative study

academic.oup.com/brain/article/122/11/2047/377239

May 20, 2024

1

A Randomized, Placebo-Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis | NEJM

www.nejm.org/doi/full/10.1056/NEJMoa044397

May 20, 2024

3

Progressive Multifocal Leukoencephalopathy

www.ninds.nih.gov/health-information/disorders/progressive-multifocal-leukoencephalopathy

May 20, 2024

1

Therapeutic uses of anti-α4-integrin (anti-VLA-4) antibodies in multiple sclerosis - PubMed

pubmed.ncbi.nlm.nih.gov/25326459/

May 20, 2024

2

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis - Nature Communications

www.nature.com/articles/s41467-019-14118-w

May 17, 2024

2

DNA of Neutrophil Extracellular Traps Binds TMCO6 to Impair CD8+ T-cell Immunity in Hepatocellular Carcinoma

aacrjournals.org/cancerres/article-abstract/84/10/1613/745317/DNA-of-Neutrophil-Extracellular-Traps-Binds-TMCO6?redirectedFrom=fulltext

May 16, 2024

1

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity

www.sciencedirect.com/science/article/pii/S1074761315003222?via%3Dihub

May 16, 2024

1

N1 versus N2 and PMN‐MDSC: A critical appraisal of current concepts on tumor‐associated neutrophils and new directions for human oncology

onlinelibrary.wiley.com/doi/full/10.1111/imr.13176

May 8, 2024

6

The regulatory roles of neutrophils in adaptive immunity - Cell Communication and Signaling

biosignaling.biomedcentral.com/articles/10.1186/s12964-019-0471-y

May 8, 2024

28

Visualization and annotation of read signal over genomic ranges with profileplyr

www.bioconductor.org/packages/devel/bioc/vignettes/profileplyr/inst/doc/profileplyr.html

Apr 24, 2024

2

The chromatin landscape of Th17 cells reveals mechanisms of diversification of regulatory and pro-inflammatory states

www.biorxiv.org/content/10.1101/2022.02.26.482041v1.full

Apr 23, 2024

18

Astrocyte CCL2 sustains immune cell infiltration in chronic experimental autoimmune encephalomyelitis

www.ncbi.nlm.nih.gov/pmc/articles/PMC4343306/

Apr 10, 2024

3

How Oxidized Low-Density Lipoprotein Activates Inflammatory Responses

www.ncbi.nlm.nih.gov/pmc/articles/PMC6527110/

Apr 10, 2024

7

Oxidized low-density lipoprotein associates with cardiovascular disease by a vicious cycle of atherosclerosis and inflammation: A systematic review and meta-analysis

www.ncbi.nlm.nih.gov/pmc/articles/PMC9885196/

Apr 10, 2024

1

The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10 - PubMed

pubmed.ncbi.nlm.nih.gov/15128827/

Apr 10, 2024

2

Resistance to Experimental Autoimmune Encephalomyelitis in Mice Lacking the Cc Chemokine Receptor (Ccr2) | Journal of Experimental Medicine | Rockefeller University Press

rupress.org/jem/article/192/7/1075/8244/Resistance-to-Experimental-Autoimmune

Apr 9, 2024

1

Absence of Monocyte Chemoattractant Protein 1 in Mice Leads to Decreased Local Macrophage Recruitment and Antigen-Specific T Helper Cell Type 1 Immune Response in Experimental Autoimmune Encephalomyelitis | Journal of Experimental Medicine | Rockefeller University Press

rupress.org/jem/article/193/6/713/25979/Absence-of-Monocyte-Chemoattractant-Protein-1-in

Apr 9, 2024

1

Cc Chemokine Receptor 2 Is Critical for Induction of Experimental Autoimmune Encephalomyelitis

www.ncbi.nlm.nih.gov/pmc/articles/PMC2193286/

Apr 9, 2024

1

NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis | Proceedings of the National Academy of Sciences

www.pnas.org/doi/10.1073/pnas.1201836109

Apr 9, 2024

2

Discovery and Pharmacological Characterization of a Novel Rodent-Active CCR2 Antagonist, INCB3344

journals.aai.org/jimmunol/article/175/8/5370/111690/Discovery-and-Pharmacological-Characterization-of

Apr 9, 2024

3

CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis—an intravital microscopy study

www.sciencedirect.com/science/article/pii/S0165572805000482?via%3Dihub

Apr 9, 2024

2

Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells

www.ncbi.nlm.nih.gov/pmc/articles/PMC2813727/

Mar 25, 2024

21

Chemokine receptor Ccr1 drives neutrophil-mediated kidney immunopathology and mortality in invasive candidiasis - PubMed

pubmed.ncbi.nlm.nih.gov/22916017/

Mar 25, 2024

2

CCL6 - an overview | ScienceDirect Topics

www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/ccl6

Mar 25, 2024

2

Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions

www.sciencedirect.com/science/article/pii/S1074761318300384

Mar 25, 2024

1

Frontiers | CCR6 and CXCR6 Identify the Th17 Cells With Cytotoxicity in Experimental Autoimmune Encephalomyelitis

www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.819224/full

Mar 20, 2024

1

Frontiers | Activated IL-1RI Signaling Pathway Induces Th17 Cell Differentiation via Interferon Regulatory Factor 4 Signaling in Patients with Relapsing-Remitting Multiple Sclerosis

www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2016.00543/full

Mar 20, 2024

1

Frontiers | IRF4 is required for migration of CD4+ T cells to the intestine but not for Th2 and Th17 cell maintenance

www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1182502/full

Mar 20, 2024

1

JunB is essential for IL-23-dependent pathogenicity of Th17 cells - Nature Communications

www.nature.com/articles/ncomms15628

Mar 20, 2024

3

JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation - Nature Communications

www.nature.com/articles/s41467-017-00380-3

Mar 20, 2024

2

New Insights into the Role of IL-1β in EAE and MS

www.ncbi.nlm.nih.gov/pmc/articles/PMC5509030/

Mar 19, 2024

1

In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed - PubMed

pubmed.ncbi.nlm.nih.gov/24953459/

Mar 19, 2024

2

Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12

www.sciencedirect.com/science/article/pii/S1074761300000704?via%3Dihub

Mar 19, 2024

1

Astrocyte-specific expression of interleukin 23 leads to an aggravated phenotype and enhanced inflammatory response with B cell accumulation in the EAE model

www.ncbi.nlm.nih.gov/pmc/articles/PMC8080359/

Mar 19, 2024

3

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain - Nature

www.nature.com/articles/nature01355

Mar 19, 2024

1

Neutrophils mediate blood-spinal cord barrier disruption in demyelinating neuroinflammatory diseases - PubMed

pubmed.ncbi.nlm.nih.gov/25049355/

Mar 19, 2024

1

Neutrophils Amplify Autoimmune Central Nervous System Infiltrates by Maturing Local APCs

journals.aai.org/jimmunol/article/191/9/4531/86668/Neutrophils-Amplify-Autoimmune-Central-Nervous

Mar 19, 2024

1

Neutrophils amplify autoimmune central nervous system infiltrates by maturing local APCs - PubMed

pubmed.ncbi.nlm.nih.gov/24062488/

Mar 19, 2024

2

A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications - PubMed

pubmed.ncbi.nlm.nih.gov/35195253/

Mar 14, 2024

1

Specifications for Thesis | Adelaide University Calendar

calendar.adelaide.edu.au/aprhdr/2018/specifications-thesis

Mar 13, 2024

2

Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells - PubMed

pubmed.ncbi.nlm.nih.gov/18278054/

Mar 8, 2024

2

Mechanisms regulating regional localization of inflammation during CNS autoimmunity

www.ncbi.nlm.nih.gov/pmc/articles/PMC3678350/

Mar 8, 2024

1

Transactivation of Classical and Nonclassical HLA Class I Genes Through the IFN-Stimulated Response Element1

journals.aai.org/jimmunol/article/163/3/1428/32737/Transactivation-of-Classical-and-Nonclassical-HLA

Mar 7, 2024

1

IL-17 and IL-17-producing cells in protection versus pathology - Nature Reviews Immunology

www.nature.com/articles/s41577-022-00746-9

Mar 7, 2024

11

IFN-γ-Induced MHC Class II Expression: Transactivation of Class II Transactivator Promoter IV by IFN Regulatory Factor-1 is Regulated by Protein Kinase C-α 1

journals.aai.org/jimmunol/article/171/8/4187/35793/IFN-Induced-MHC-Class-II-Expression

Mar 4, 2024

2

T Helper 1 Cell - an overview | ScienceDirect Topics

www.sciencedirect.com/topics/medicine-and-dentistry/t-helper-1-cell

Mar 3, 2024

1

Type 2 immunity in tissue repair and fibrosis - Nature Reviews Immunology

www.nature.com/articles/nri.2017.90

Mar 3, 2024

1

Frontiers | Conventional and pathogenic Th2 cells in inflammation, tissue repair, and fibrosis

www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.945063/full

Mar 3, 2024

20

Savant Energy

myaccount.savantenergy.com.au/

Mar 3, 2024

1

T cells in health and disease - Signal Transduction and Targeted Therapy

www.nature.com/articles/s41392-023-01471-y

Feb 29, 2024

32

Runx2 Overexpression Enhances Potency and Counteracts Exhaustion in CD8+ CAR T Cells

ashpublications.org/blood/article/142/Supplement%201/2082/500036/Runx2-Overexpression-Enhances-Potency-and

Feb 24, 2024

2

The Transcription Factor Runx2 Is Required for Long-Term Persistence of Antiviral CD8+ Memory T Cells - PubMed

pubmed.ncbi.nlm.nih.gov/30264035/

Feb 24, 2024

1

The Transcription Factor Runx2 Is Required for Long-Term Persistence of Antiviral CD8+ Memory T Cells

journals.aai.org/immunohorizons/article/2/7/251/3851/The-Transcription-Factor-Runx2-Is-Required-for

Feb 24, 2024

2

Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2 - Nature Communications

www.nature.com/articles/s41467-022-28172-4

Feb 6, 2024

9

Integrin α3 promotes Th17 cell polarization and extravasation during autoimmune neuroinflammation.

www.ncbi.nlm.nih.gov/pmc/articles/PMC10821720/

Feb 1, 2024

2

0

Neurodegeneration in Multiple Sclerosis: Symptoms of Silent Progression, Biomarkers and Neuroprotective Therapy—Kynurenines Are Important Players

URL
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201043/

Highlights & Notes

There is accumulating evidence that the other hallmark process, neurodegeneration, is not simply present from the very beginning of the disease, but might even be the initiator of the pathological cascade resulting in MS.