Systemic Administration of Tripeptidyl Peptidase I in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis: Effect of Glycan Modification
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May 31, 2026
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患者1人約3億円の遺伝子治療を「誰もが使える医療」へ、ノーベル賞科学者が挑むエコシステム構想 | Forbes JAPAN 公式サイト（フォーブス ジャパン）
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Mar 15, 2026
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Just a moment...
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www.cell.com/cell/fulltext/S0092-8674(25)01425-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867425014254%3Fshowall%3Dtrue
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Cell-Type Atlas of Brain Lysosomal Proteins May Clarify Neurological Disorders
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Lysosomal Brain Protein Atlas
brainresilience.stanford.edu/lysosomal-brain-protein-atlas
Jan 30, 2026
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Treatment of Inherited Eye Defects by Systemic Hematopoietic Stem Cell Transplantation | IOVS | ARVO Journals
iovs.arvojournals.org/article.aspx?articleid=2469222
Jan 12, 2026
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Frontiers | The Contribution of Microglia to the Development and Maturation of the Visual System
www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2021.659843/full
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www.researchgate.net/publication/336168617_Roles_of_Drug_Transporters_in_Blood-Retinal_Barrier/figures?lo=1&utm_medium=&utm_campaign=
Jan 12, 2026
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網膜 - 脳科学辞典
bsd.neuroinf.jp/wiki/%E7%B6%B2%E8%86%9C
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ミュラーグリア - 脳科学辞典
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網膜色素変性の過蛍光リング – 目医者情報
meisha.info/archives/744
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網膜色素変性 – 目医者情報
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CNS infection and immune privilege - Nature Reviews Neuroscience
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2025 FDA approvals
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BioMarin to buy Amicus Therapeutics for $4.8B, bringing together rare disease biotechs
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An AAV variant selected through NHP screens robustly transduces the brain and drives secreted protein expression in NHPs and mice
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Latus Bio Announces IND Clearance of LTS-101 for CLN2 Disease and Receipt of Fast Track, Orphan Drug, and Rare Pediatric Disease Designations
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Brain-Directed AAV Gene Therapy Rescues a Mouse Model of the CLN5 Form of Neuronal Ceroid Lipofuscinosis Disease and Normalizes a Blood Plasma Biomarker of Neurodegeneration | Human Gene Therapy
www.liebertpub.com/doi/10.1177/10430342251403448
Jan 4, 2026
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GEN Editors Reflect on Six of the Biggest Stories of the Year
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Purification and characterisation of a tripeptidyl aminopeptidase I from rat spleen
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Structure of Tripeptidyl-peptidase I Provides Insight into the Molecular Basis of Late Infantile Neuronal Ceroid Lipofuscinosis *
www.jbc.org/article/S0021-9258(19)81812-4/fulltext
Jan 2, 2026
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Staying Current in Data Science and Computational Biology: 2026 Edition
blog.stephenturner.us/p/staying-current-in-data-science-and-computational-biology-2026
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資料112－1 ミトコンドリア置換研究について（山田満稔慶應義塾大学講師提出資料） - 1421121_002.pdf
www.mext.go.jp/kaigisiryo/2019/09/__icsFiles/afieldfile/2019/09/11/1421121_002.pdf
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Crystal Structure and Autoactivation Pathway of the Precursor Form of Human Tripeptidyl-peptidase 1, the Enzyme Deficient in Late Infantile Ceroid Lipofuscinosis *
www.jbc.org/article/S0021-9258(19)81813-6/fulltext
Dec 28, 2025
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h-4065-PAR-EN - brineura-epar-public-assessment-report_en.pdf
www.ema.europa.eu/en/documents/assessment-report/brineura-epar-public-assessment-report_en.pdf
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761052Orig1s000SumR.pdf
www.accessdata.fda.gov/drugsatfda_docs/nda/2017/761052Orig1s000SumR.pdf
Dec 28, 2025
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FOCUS: an AI-assisted reading workflow for information overload | Nature Biotechnology
www.nature.com/articles/s41587-025-02947-8
Dec 20, 2025
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Mutations in Mitochondrial Genes Ameliorate Pathology in Friedreich’s Ataxia Model
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Next-Gen CAR T Cells Destroy Cancer Cells with Fewer Toxic Effects in Mice
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Just a moment...
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Dec 13, 2025
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