Diastereomers | Summary and Q&A

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April 25, 2018
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The Organic Chemistry Tutor
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Diastereomers

TL;DR

Diastereomers are stereoisomers that have different spatial arrangements but share the same connectivity, and can be drawn by changing some but not all chiral centers.

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Key Insights

  • ❓ Diastereomers have different spatial arrangements but share the same connectivity.
  • 💱 Changing some but not all of the chiral centers can generate diastereomers.
  • 🏃 Diastereomers can be cis/trans isomers if the arrangement is around a double bond.
  • 💱 If all chiral centers are changed, the molecule becomes an enantiomer.
  • 〽️ Diastereomers can be drawn by altering the configuration of specific chiral centers.
  • 👾 Diastereomers can have different arrangements of groups in space.
  • 🧘 Diastereomers can be identified by the change in position of specific functional groups.

Transcript

now let's talk about diastereomers how can we draw the diastereomer of this molecule how can we draw to draw a diastereomer of a molecule all you need to do is change some but not all of the chiral centers so let's change the first chiral center the o h is on the wedge let's put it on a dash and so this is the dice term of this molecule now notice ... Read More

Questions & Answers

Q: What are diastereomers?

Diastereomers are a type of stereoisomer that have the same connectivity but different spatial arrangements in space.

Q: How can diastereomers be drawn?

To draw a diastereomer, some but not all of the chiral centers in the molecule need to be changed. This alters the spatial arrangement of groups in the molecule.

Q: What is the difference between cis/trans isomers and diastereomers?

Cis/trans isomers are a subcategory of diastereomers, where the arrangement of groups around a double bond is different. Diastereomers encompass all stereoisomers with different spatial arrangements.

Q: Is it possible to have multiple diastereomers of a molecule?

Yes, it is possible to have multiple diastereomers of a molecule by changing different combinations of chiral centers while keeping others unchanged.

Summary & Key Takeaways

  • Diastereomers are a type of stereoisomer that have different spatial arrangements but the same connectivity.

  • To draw a diastereomer, only some of the chiral centers in the molecule need to be changed.

  • Diastereomers can be identified by their different arrangements of groups in space.

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