11. Differentiation of the brain vesicles, part 2: Developmental distortions; evolution of... | Summary and Q&A

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October 4, 2023
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11. Differentiation of the brain vesicles, part 2: Developmental distortions; evolution of...

TL;DR

The content discusses the developmental changes and distortions in the hindbrain, particularly in the cerebellum, and the role of inputs and outputs in the pots (bridge).

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Key Insights

  • 🥺 The hindbrain undergoes changes in structure and size during development, leading to distortions in the adult brain.
  • 🖐️ The cerebellum plays a crucial role in coordinating outputs from the neocortex and receives inputs from various sensory systems.
  • 🦛 The pots serves as a bridge between the hindbrain and the cerebellum, transmitting inputs from the hindbrain to the cerebellar cortex.
  • 😮 The rhombic lip is a transient structure that gives rise to cells migrating into the cerebellum and other hindbrain structures, contributing to its developmental changes and distortions.
  • 🔠 The size of the cerebellum is influenced by the size of the neocortex, which requires coordination from the cerebellum to adjust and synchronize inputs from different sensory systems.
  • 👅 The hindbrain's structural distortions are caused by the growth and specialization of cell groups, such as gustatory neurons in animals with taste specialization.
  • 🖐️ The pots, located in the rostral hindbrain, serves as a distinct bridge between the hindbrain and the cerebellum, playing a crucial role in transmitting inputs to the cerebellar cortex.

Transcript

the following content is provided under a Creative Commons license your support will help MIT opencourseware continue to offer high quality educational resources for free to make a donation or view additional materials from hundreds of MIT courses visit MIT opencourseware at ocw.mit.edu a little more about the hindbringing about these I want to tal... Read More

Questions & Answers

Q: What is the pots and why is it called a bridge?

The pots is a structure located in the rostral hindbrain that is wider than the rest of the hindbrain. It is called a bridge because when viewed from the ventral side, it appears as a distinct and larger structure that connects the hindbrain to the cerebellum.

Q: What causes quantitative distortions in the hindbrain's structural layout?

The hindbrain's structural distortions are caused by changes in the size of structures, particularly the cell groups that grow and become big, distorting the hindbrain. In certain animals, like fish with taste specialization, the my brainstem is distorted due to the growth of gustatory neurons.

Q: Why does the cerebellum become large in primates?

The cerebellum becomes large in primates due to the presence of a large neocortex. The neocortex requires coordination from the cerebellum to adjust and coordinate inputs from various sensory systems, such as cochleceptive, somatosensory, and visual inputs.

Q: What role does the rhombic lip play in the development of the hindbrain?

The rhombic lip is a structure seen during the development of the rostral hindbrain. It serves as a source of cells that migrate and form the cerebellum and other structures in the hindbrain. These migrations contribute to the distortions and complexity in the hindbrain's structural layout.

Summary & Key Takeaways

  • The hindbrain undergoes changes in structure, size, and migration of cells, leading to distortions in the adult brain, especially in specialized creatures like fish with taste specialization.

  • The cerebellum, located in the rostral hindbrain, is characterized by the pots, which is wider than the rest of the hindbrain due to myelinated fibers and contains the pontine gray matter.

  • The pots serves as a bridge between the hindbrain and the cerebellum, receiving inputs from various sensory systems and projecting them to the cerebellar cortex.

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