Molecular structure of fructose | Macromolecules | Biology | Khan Academy | Summary and Q&A

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July 14, 2015
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Molecular structure of fructose | Macromolecules | Biology | Khan Academy

TL;DR

Glucose and fructose are structural isomers, with the main difference being the position of the carbonyl group. Fructose is the sweetest monosaccharide and is a key component of sucrose.

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Key Insights

  • 💄 Glucose and fructose are both monosaccharides with the same chemical formula (C6H12O6) but different structures, making them isomers.
  • 👥 Glucose has a carbonyl group at the first carbon, while fructose has it at the second carbon.
  • 🍌 Fructose is the sweetest of all the sugars and is commonly found in fruits.
  • 🚰 Sucrose, commonly referred to as table sugar, is a disaccharide composed of glucose and fructose.
  • 💁 Glucose and fructose can form cyclic structures, with glucose often existing as a pyranose and fructose as a furanose.
  • 💁 The formation of sucrose involves the dehydration synthesis reaction, where the oxygen on the first carbon of glucose forms a glycosidic bond with the second carbon of fructose.
  • 🖐️ The cyclic forms of glucose and fructose play a role in their biological functions and interactions with other molecules.

Transcript

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Questions & Answers

Q: What is the main difference between glucose and fructose?

The main difference between glucose and fructose is the position of the carbonyl group. Glucose has a carbonyl group at the first carbon, while fructose has it at the second carbon.

Q: Why is fructose referred to as fruit sugar?

Fructose is commonly known as fruit sugar because it is found in high quantities in fruits and gives them their sweet taste.

Q: How do glucose and fructose combine to form sucrose?

Glucose and fructose combine through a glycosidic bond to form sucrose. The oxygen in the hydroxyl group on the first carbon of glucose forms a bond with the second carbon of fructose.

Q: What are the cyclic forms of glucose and fructose?

Glucose is most commonly found in a six-member ring called a pyranose, while fructose is typically found in a five-member ring called a furanose. However, fructose can also exist in a pyranose form.

Summary & Key Takeaways

  • Glucose and fructose are both monosaccharides with the same chemical formula but different structures, making them structural isomers.

  • The main difference between glucose and fructose is the position of the carbonyl group - glucose has it at the first carbon, while fructose has it at the second carbon.

  • Fructose is the sweetest of all the sugars and is commonly known as fruit sugar. It is a key component of table sugar (sucrose), which is formed through a glycosidic bond between glucose and fructose.

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