Is the cure for cancer already inside us? | Dr. Shana Kelley | TEDxChicago | Summary and Q&A

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February 4, 2024
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Is the cure for cancer already inside us? | Dr. Shana Kelley | TEDxChicago

TL;DR

Researchers have developed a high-throughput cell processing technology to find and collect rare immune cells from the blood, which could potentially be used as a new treatment for cancer.

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Key Insights

  • 👻 High-throughput cell processing technology allows for the efficient and fast analysis of billions of cells, enabling the search for rare immune cells.
  • 🥺 Tumor-infiltrating lymphocytes (TILs) therapy has shown significant success in treating advanced melanoma, leading researchers to explore similar approaches for other cancers.
  • 👶 The discovery of circulating tumor-reactive lymphocytes (CTRLs) in the blood provides a new starting material for cell therapy, potentially making the treatment more accessible and practical.

Transcript

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Questions & Answers

Q: What is the main goal of the researchers in this study?

The researchers aim to find and collect rare immune cells from the blood that have the potential to recognize and eliminate cancer cells, with the goal of developing a new treatment for cancer.

Q: What was the main challenge in the cell processing speed?

The previous cell processing speed was too slow, as cells were analyzed one at a time. This hindered the search for rare immune cells, as it would take weeks to process a tube of blood.

Q: What is the potential of immunotherapy in cancer treatment?

Immunotherapy has shown promising results in using the immune system to fight diseases like cancer. By boosting the patient's immune system or providing extra immune cells, it allows for the elimination of tumor cells.

Q: What are circulating tumor-reactive lymphocytes (CTRLs)?

CTRLs are immune cells that accumulate in tumor tissue and can be found in the blood. These rare immune cells have the potential to control tumor progression and can be used as a starting material for cell therapy.

Summary & Key Takeaways

  • Researchers have developed a system to find and collect rare disease-fighting immune cells from the human body, with the potential for cancer treatment.

  • The technology allows for the processing of billions of cells in a short amount of time, overcoming previous limitations.

  • Tumor-infiltrating lymphocytes (TILs) therapy has shown promising results in clinical trials, and researchers are now exploring the use of circulating tumor-reactive lymphocytes (CTRLs) as a starting material for cell therapy.

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