Diastereomers | Summary and Q&A

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April 25, 2018
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Diastereomers

TL;DR

Diastereomers are stereoisomers that have different spatial arrangements but share the same connectivity, and can be drawn by changing some but not all chiral centers.

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Questions & Answers

Q: What are diastereomers?

Diastereomers are a type of stereoisomer that have the same connectivity but different spatial arrangements in space.

Q: How can diastereomers be drawn?

To draw a diastereomer, some but not all of the chiral centers in the molecule need to be changed. This alters the spatial arrangement of groups in the molecule.

Q: What is the difference between cis/trans isomers and diastereomers?

Cis/trans isomers are a subcategory of diastereomers, where the arrangement of groups around a double bond is different. Diastereomers encompass all stereoisomers with different spatial arrangements.

Q: Is it possible to have multiple diastereomers of a molecule?

Yes, it is possible to have multiple diastereomers of a molecule by changing different combinations of chiral centers while keeping others unchanged.

Summary & Key Takeaways

  • Diastereomers are a type of stereoisomer that have different spatial arrangements but the same connectivity.

  • To draw a diastereomer, only some of the chiral centers in the molecule need to be changed.

  • Diastereomers can be identified by their different arrangements of groups in space.

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