Novel stimuli evoke excess activity in the mouse primary visual cortex | PNAS thumbnail
Novel stimuli evoke excess activity in the mouse primary visual cortex | PNAS
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We show that this phenomenon can be described by a model of cascading adaptation To explore how neural circuits represent novel versus familiar inputs, we presented mice with repeated sets of images with novel images sparsely substituted When a new image set was repeatedly presented, a majority of n
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Top Highlights

  • We show that this phenomenon can be described by a model of cascading adaptation
  • To explore how neural circuits represent novel versus familiar inputs, we presented mice with repeated sets of images with novel images sparsely substituted
  • When a new image set was repeatedly presented, a majority of neurons had similarly elevated activity for the first few presentations, which decayed to steady state with a time constant of 1.4 ± 0.4 s.
  • adaptation
  • slower decay of activity

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