GRK5 is a regulator of fibroblast activation and cardiac fibrosis | PNAS
www.pnas.org
GRK5 is highly expressed and active in cardiac fibroblasts; angiotensin II (AngII)-mediated fibroblast activation decreased fibrosis and cardiac hypertrophy nuclear translocation of GRK5 is involved in fibroblast activation GRK5 is a major GRK isoform expressed in the heart and it has been shown to
1 Users
0 Comments
14 Highlights
0 Notes
Top Highlights
- GRK5 is highly expressed and active in cardiac fibroblasts;
- angiotensin II (AngII)-mediated fibroblast activation
- decreased fibrosis and cardiac hypertrophy
- nuclear translocation of GRK5 is involved in fibroblast activation
- GRK5 is a major GRK isoform expressed in the heart and it has been shown to be up-regulated in the myocardium of HF patients
Domain
Ready to highlight and find good content?
Glasp is a social web highlighter that people can highlight and organize quotes and thoughts from the web, and access other like-minded people’s learning.