Rewritable digital data storage in live cells via engineered control of recombination directionality | PNAS
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By carefully tuning and integrating the expression of competing recombinase functions, we were able to develop a first reliable and rewritable DNA inversion-based data storage system that works in vivo The DNA inversion RAD module developed here should be translatable to applications requiring stabl
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- By carefully tuning and integrating the expression of competing recombinase functions, we were able to develop a first reliable and rewritable DNA inversion-based data storage system that works in vivo
- The DNA inversion RAD module developed here should be translatable to applications requiring stable long-term data storage (for example, replicative aging) or under challenging conditions (for example, clinical or environmental contexts requiring in situ diagnosis or ex post facto reporting via PCR or DNA sequencing). Given the natural phage recomb...
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