Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production | Proceedings of the National Academy of Sciences
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Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production mtDNA mutator mice accumulate mtDNA mutations in an approximately linear manner amount of ROS produced was normal no increased sensitivity to oxidative stress-induced cell death was observed in mouse
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- Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
- mtDNA mutator mice accumulate mtDNA mutations in an approximately linear manner
- amount of ROS produced was normal
- no increased sensitivity to oxidative stress-induced cell death was observed in mouse embryonic fibroblasts from mtDNA mutator mice
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