Targeted overexpression of protein kinase C β2 isoform in myocardium causes cardiomyopathy | Proceedings of the National Academy of Sciences thumbnail
Targeted overexpression of protein kinase C β2 isoform in myocardium causes cardiomyopathy | Proceedings of the National Academy of Sciences
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activation of the PKCβ2 isoform can cause specific cardiac cellular and functional changes leading to cardiomyopathy of diabetic or nondiabetic etiolog activation of the PKCβ isoform can cause cardiac dysfunctions, we have established lines of transgenic mice with the specific overexpression of PKCβ
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  • activation of the PKCβ2 isoform can cause specific cardiac cellular and functional changes leading to cardiomyopathy of diabetic or nondiabetic etiolog
  • activation of the PKCβ isoform can cause cardiac dysfunctions, we have established lines of transgenic mice with the specific overexpression of PKCβ2 isoform in the myocardium
  • proteins exhibited left ventricular hypertrophy, cardiac myocyte necrosis, multifocal fibrosis, and decreased left ventricular performance without vascular lesions

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