Both Northern blot analysis and reverse transcriptase (RT)-driven in situ PCR (RT-in situ PCR) studies demonstrated that inducible NO synthase (iNOS) mRNA was present in the brain tissues from MS patients but was absent in equivalent tissues from normal controls
combination with immunohistochemistry
iNOS mRNA was detectable in the brains of 100% of the CNS tissues from seven MS patients examined but in none of the three normal brains.
. We have examined post-mortem brain tissues collected from patients previously diagnosed with
ducible NO synthase (iNOS) mRNA was present in the brain tissues from MS patient
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