Neutral lysophosphatidylcholine mediates α-synuclein-induced synaptic vesicle clustering | Proceedings of the National Academy of Sciences thumbnail
Neutral lysophosphatidylcholine mediates α-synuclein-induced synaptic vesicle clustering | Proceedings of the National Academy of Sciences
www.pnas.org
we found that lysoPC significantly increases the number and the size of v-vesicle clusters induced by α-Syn (Fig. 3 C and D) in the absence of anionic lipids. by impairing the binding to lysoPC, the A30P mutation diminished α-Syn-mediated vesicle clustering
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  • we found that lysoPC significantly increases the number and the size of v-vesicle clusters induced by α-Syn (Fig. 3 C and D) in the absence of anionic lipids.
  • by impairing the binding to lysoPC, the A30P mutation diminished α-Syn-mediated vesicle clustering

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synuclein
lipid
membrane binding

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