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Cas9-expressing chickens and pigs as resources for genome editing in livestock
www.pnas.org
Genetically modified animals are crucial for functional studies and translational biomedical research the generation of genome-edited large animals is time consuming and inefficient. we report the generation of transgenic pigs and chickens that ubiquitously express Cas9 nuclease. Genome editing can
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Genetically modified animals are crucial for functional studies and translational biomedical research
the generation of genome-edited large animals is time consuming and inefficient.
we report the generation of transgenic pigs and chickens that ubiquitously express Cas9 nuclease.
Genome editing can now easily be carried out in vivo in specific organs or tissues without the need to generate germline-modified animals.
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www.pnas.org
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