Noncontiguous operon is a genetic organization for coordinating bacterial gene expression thumbnail
Noncontiguous operon is a genetic organization for coordinating bacterial gene expression
www.pnas.org
Here, we report the existence of a higher level of organization in operon structure that we named noncontiguous operon and consists in an operon containing a gene(s) that is transcribed in the opposite direction to the rest of the operon. However, these features are predisposed by the classical oper
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  • Here, we report the existence of a higher level of organization in operon structure that we named noncontiguous operon and consists in an operon containing a gene(s) that is transcribed in the opposite direction to the rest of the operon.
  • However, these features are predisposed by the classical operon concept, and, consequently, the identification of variations in genetic organization inside operon structure through bioinformatic predictions has been very limited.
  • n unexpected finding unraveled by the precise determination of transcript boundaries is that very often convergent operons overlap at their 3′ end (tail to tail) and divergent operons overlap at their 5′ end (head to head). In these situations, the mRNA contributes to the expression of operon genes, and at th
  • As expected
  • esults showed that

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