the D-aa-tRNA deacylase (DTD) enzyme is nearly universally conserved
and functions to remove D-amino acids that have been misacylated onto tRNA
Once an aa-tRNA has been incorporated into the ribosomal aa-tRNA binding (A) site, the ribosome positions the carbonyl carbon of the ester bond linking the nascent polypeptide to the peptidyl-tRNA bound at the ribosomal peptidyl-tRNA binding (P) site for nucleophilic attack by the α-amino group of the amino acid moiety of the newly incorporated A-s...
Glasp is a social web highlighter that people can highlight and organize quotes and thoughts from the web, and access other like-minded people’s learning.