Top Highlights

• replaces one animal species with a less developed one
• researchers successfully created in vitro methods to identify severe eye irritants and substances that could cause allergic contact dermatitis.
• substitutes traditional animal models with non-animal systems such as computer models or biochemical or cell-based systems
• decreases the number of animals required for testing to a minimum while still achieving testing objectives.
• eliminates pain or distress in animals, or enhances animal well-being, such as by providing better housing or enrichment

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