Universal DNA methylation age across mammalian tissues - Nature Aging thumbnail
Universal DNA methylation age across mammalian tissues - Nature Aging
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Age deviations correlate with human mortality risk identified specific cytosines with methylation levels that change with age across numerous species aging is evolutionarily conserved and intertwined with developmental processes across all mammals mammalian methylation array, which we recently devel
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  • Age deviations correlate with human mortality risk
  • identified specific cytosines with methylation levels that change with age across numerous species
  • aging is evolutionarily conserved and intertwined with developmental processes across all mammals
  • mammalian methylation array, which we recently developed to profile methylation levels of up to 36,000 CpG sites with flanking DNA sequences highly conserved across the mammalian class
  • 11,754 samples from 59 tissue types, originating from 185 mammalian species

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