Frontiers | HMGA2 promotes nasopharyngeal carcinoma progression and is associated with tumor resistance and poor prognosis thumbnail
Frontiers | HMGA2 promotes nasopharyngeal carcinoma progression and is associated with tumor resistance and poor prognosis
www.frontiersin.org
This may occur by direct binding of HMGA2 to cyclinA2’s cyclinA2-reactive elements, displacing the p120E4F-containing complex from cyclinA2, thereby inducing cyclinA2 expression and accelerating cell cycle progression ( Studies have shown that HMGA2 can act as a regulator of cell proliferation, and
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  • This may occur by direct binding of HMGA2 to cyclinA2’s cyclinA2-reactive elements, displacing the p120E4F-containing complex from cyclinA2, thereby inducing cyclinA2 expression and accelerating cell cycle progression (
  • Studies have shown that HMGA2 can act as a regulator of cell proliferation, and its expression is increased in many types of human tumor tissue

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