Frontiers | Cytotoxic T Cell-Derived Granzyme B Is Increased in Severe Plasmodium Falciparum Malaria thumbnail
Frontiers | Cytotoxic T Cell-Derived Granzyme B Is Increased in Severe Plasmodium Falciparum Malaria
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Importantly, we found a positive correlation between CD3+CD8+GrzB+ T cells and parasitemia. This suggests that an increased antigen density influences the proportion of activated T cells producing GrzB. The strong GrzB production by CD8+ T cells, however fails to control or lower the parasitaemia in
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  • Importantly, we found a positive correlation between CD3+CD8+GrzB+ T cells and parasitemia. This suggests that an increased antigen density influences the proportion of activated T cells producing GrzB. The strong GrzB production by CD8+ T cells, however fails to control or lower the parasitaemia in P. falciparum malaria in our patients. This is in...

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