Frontiers | The Complement System of Agnathans
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Agnathan complement system. Lectin pathway: MBL forms a complex with MBL-associated serine proteases (MASP) (MASP-1, MASP-A, and MASP-B). C1q forms a complex with MASP-A and possibly with MASP-1 and MASP-B. Upon binding of the MBL-MASP or C1q-MASP complexes to carbohydrates on pathogens, MASP change
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- Agnathan complement system. Lectin pathway: MBL forms a complex with MBL-associated serine proteases (MASP) (MASP-1, MASP-A, and MASP-B). C1q forms a complex with MASP-A and possibly with MASP-1 and MASP-B. Upon binding of the MBL-MASP or C1q-MASP complexes to carbohydrates on pathogens, MASP changes from the unactivated form to the active form. As...
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