Frontiers | Cell polarity signalling at the birth of multicellularity: What can we learn from the first animals
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ownstream from the core PCP signalling, the PCP protein Dishevelled interacts with Lgl, Cdc42, RhoA and Rac1. AGUK genes extend past the metazoan lineage and have been identified in the choanoflagellate M. brevicollis and protist C. owczarzaki (Mendoza et al., 2010). Th h tight junctions are ‘strict
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- ownstream from the core PCP signalling, the PCP protein Dishevelled interacts with Lgl, Cdc42, RhoA and Rac1.
- AGUK genes extend past the metazoan lineage and have been identified in the choanoflagellate M. brevicollis and protist C. owczarzaki (Mendoza et al., 2010). Th
- h tight junctions are ‘stricto-sensu’ vertebrate specific, genes associated with tight junctions have been identified in invertebrates, basal metazoans and choanoflagellates and hence referred to as ‘claudin-like
- Phylogenetic analysis of prickle and prickle-like genes reveals an ancestor of the gene in choanoflagellates.
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