Human Engineered Heart Tissue Models for Disease Modeling and Drug Discovery
www.frontiersin.org
mechanical load on CMs enhances their maturation by auxotonic contraction, stretching, and afterload in the tissue hydrogel scaffold-based 3D cardiac models such as engineered cardiac/heart tissues (ECT/EHT), engineered human myocardium (EHM), biowires, and HoC unidirectional force of contraction se
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- mechanical load on CMs enhances their maturation
- by auxotonic contraction, stretching, and afterload in the tissue
- hydrogel scaffold-based 3D cardiac models such as engineered cardiac/heart tissues (ECT/EHT), engineered human myocardium (EHM), biowires, and HoC
- unidirectional force of contraction
- self-assembled, easy to fabricate, and do not require specific equipment
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