Conservation of neuron-astrocyte coordinated activity among sensory processing centers of the developing brain thumbnail
Conservation of neuron-astrocyte coordinated activity among sensory processing centers of the developing brain
www.biorxiv.org
in vivo simultaneous imaging of neuronal and astrocyte calcium activity in awake mouse pups waves of retinal ganglion cell activity induce spatially and temporally correlated waves of astrocyte activity in the superior colliculus that depend on metabotropic glutamate receptors mGluR5 and mGluR3 peak
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  • in vivo simultaneous imaging of neuronal and astrocyte calcium activity in awake mouse pups
  • waves of retinal ganglion cell activity induce spatially and temporally correlated waves of astrocyte activity in the superior colliculus that depend on metabotropic glutamate receptors mGluR5 and mGluR3
  • peaked more than one second after neuronal events.
  • burst firing of retinal ganglion cells (RGCs) is first induced by the release of acetylcholine by a subset of amacrine cells, triggering a gap-junction dependent propagating wave of correlated activity among primary sensory neurons that project to the brain
  • the assembly of functional circuits depends crucially on the coincident maturation of astrocytes,

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