Electrophysiological signatures of visual recognition memory across all layers of mouse V1
www.biorxiv.org
confirmed that V1 glutamatergic neurons play a key role in SRP by using an intersectional genetic strategy to knock out NMDARs in only principal cells. targeted NMDARs in a genetically defined subset of excitatory neurons in L6 that are known to influence PV+ inhibition in L4 Namely, phase reversals
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- confirmed that V1 glutamatergic neurons play a key role in SRP by using an intersectional genetic strategy to knock out NMDARs in only principal cells.
- targeted NMDARs in a genetically defined subset of excitatory neurons in L6 that are known to influence PV+ inhibition in L4
- Namely, phase reversals of familiar stimuli evoke larger amplitude VEPs across all layers compared to novel stimuli.
- there is elevated peak L4 unit activity immediately following each phase reversal of the familiar stimulus
- his increase in peak firing rate is also apparent in superficial, middle, and deep layers.
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