Satellite glia are essential modulators of sympathetic neuron survival, activity, and autonomic function thumbnail
Satellite glia are essential modulators of sympathetic neuron survival, activity, and autonomic function
www.biorxiv.org
in promoting axon regeneration after peripheral nerve injury in vivo (Avraham et al., 2020). Brain Lipid Binding Protein (BLBP), which encodes for a fatty acid transporter, is one of the most highly expressed transcripts in mouse satellite glial cells Despite the decrease in neuronal numbers, sympat
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  • in promoting axon regeneration after peripheral nerve injury in vivo (Avraham et al., 2020).
  • Brain Lipid Binding Protein (BLBP), which encodes for a fatty acid transporter, is one of the most highly expressed transcripts in mouse satellite glial cells
  • Despite the decrease in neuronal numbers, sympathetic axon innervation was maintained in target organs in BLBP:iDTA mice, when assessed by whole-mount TH immunostaining in iDISCO-cleared tissues and light sheet microscopy (Figures S2A-C)
  • suggesting differential regulation of TH distribution in neuronal soma vs. axons.

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