Identification of a stereotypic molecular arrangement of endogenous glycine receptors at spinal cord synapses
elifesciences.org
Thus far, the nanoscale organization of GlyRs underlying the different network specificities has not been defined. Here, we have quantitatively characterized the molecular arrangement and ultra-structure of glycinergic synapses in spinal cord tissue using quantitative super-resolution correlative li
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- Thus far, the nanoscale organization of GlyRs underlying the different network specificities has not been defined. Here, we have quantitatively characterized the molecular arrangement and ultra-structure of glycinergic synapses in spinal cord tissue using quantitative super-resolution correlative light and electron microscopy. We show that endogeno...
- receptors at excitatory and inhibitory synapses are organized within sub-synaptic domains (SSDs) that are aligned with presynaptic elements of the active zone (AZ)
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