The driver for the evolution of adhesion in our model is collective chemotaxis. This is reminiscent of the aggregate phase of the life cycle of Dictyostelium discoideum
nformation about the direction of the gradient is transmitted mechanically within cell clusters in our mode
waves of cAMP secretion that travel through the slug.
s, computational modelling has shown that long-range chemical signalling coupled to cells’ differential adhesion suffices to reproduce D. discoideum’s migration
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