The Toll pathway inhibits tissue growth and regulates cell fitness in an infection-dependent manner
elifesciences.org
Since Toll signaling is a key mediator for the immune response, it is possible that a subliminal pathway activity level stems from chronic exposure to pathogens, due to typically unsterile working conditions. Under extra-pathogen conditions Cactus-dependent overgrowth was further enhanced, but suppr
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- Since Toll signaling is a key mediator for the immune response, it is possible that a subliminal pathway activity level stems from chronic exposure to pathogens, due to typically unsterile working conditions.
- Under extra-pathogen conditions Cactus-dependent overgrowth was further enhanced, but suppressed under axenic conditions (Figure 3A–B’’, quantified in Figure 3D).
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