Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection
elifesciences.org
Retinol plays a vital role in the physiological response to microbial challenge. Retinol is derived from dietary vitamin A and can be converted enzymatically to retinoic acid, which complexes with nuclear receptors to regulate gene transcription programs in cells (Germain et al., 2006). In this way,
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- Retinol plays a vital role in the physiological response to microbial challenge. Retinol is derived from dietary vitamin A and can be converted enzymatically to retinoic acid, which complexes with nuclear receptors to regulate gene transcription programs in cells (Germain et al., 2006). In this way, retinol promotes the maturation of innate immune ...
- Expression of SAAs is strongly induced by microbial exposure.
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