Estimating Time to the Common Ancestor for a Beneficial Allele thumbnail
Estimating Time to the Common Ancestor for a Beneficial Allele
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What is the molecular mechanism by which the variant affects organismal traits and fitness (Dalziel et al. 2009)?; what is the selective mechanism responsible for allelic differences in fitness?; did the variant arise by mutation more than once (Elmer and Meyer 2011)?; and when did each unique insta
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  • What is the molecular mechanism by which the variant affects organismal traits and fitness (Dalziel et al. 2009)?; what is the selective mechanism responsible for allelic differences in fitness?; did the variant arise by mutation more than once (Elmer and Meyer 2011)?; and when did each unique instance of the variant arise and spread (Slatkin and R...
  • Understanding these dates can give indirect evidence regarding the selective pressure that may underlie the adaptation
  • n humans, for example, dispersal across the globe has resulted in the occupation of a wide variety of habitats, and in several cases, selection in response to specific ecological pressures appears to have taken place.
  • stochastic outcome of survival,

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Human genomics

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