Top Highlights

• It’s a Y Combinator-backed nonprofit entirely funded by phil- anthropic donations
• Many conventional approaches to making the world a better place don’t actually work
• One of the most important things we’ve learned is that if lots of people already work on an issue, the best opportunities to help are more likely to have already been taken.
• At the same time, we found real ways to help with important neglected problems.
• Which jobs might get ruled out? We made some guesses at jobs that involve causing a significant amount of negative impact

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