Step aside San Francisco, New York and Boston. The next potential hub of digital health innovation may be in Israel. 

Rochester, Minnesota-based Mayo aligned with Sheba in June 2022 when the two organizations agreed to share data from startups at Sheba’s innovation center and Mayo's Platform Accelerate program.

For a country with roughly the same number of people as New Jersey--roughly 9.3 million--Israel is home to more than 6,000 startups, according to a report from consulting firm Deloitte. Innovation is embedded in the country's culture, which makes it an ideal place to launch a startup, said Yonatan Adiri, CEO of Tel Aviv-based Healthy.io, which has developed a smartphone app that can test for kidney disease.